Olarerin-George Anthony O, Jaffrey Samie R
Department of Pharmacology, Weill Medical College, Cornell University, New York, NY, USA.
Bioinformatics. 2017 May 15;33(10):1563-1564. doi: 10.1093/bioinformatics/btx002.
An increasing number of studies are mapping protein binding and nucleotide modifications sites throughout the transcriptome. Often, these sites cluster in certain regions of the transcript, giving clues to their function. Hence, it is informative to summarize where in the transcript these sites occur. A metagene is a simple and effective tool for visualizing the distribution of sites along a simplified transcript model. In this work, we introduce MetaPlotR, a Perl/R pipeline for creating metagene plots.
The code and associated tutorial are available at https://github.com/olarerin/metaPlotR .
越来越多的研究正在绘制整个转录组中的蛋白质结合位点和核苷酸修饰位点。通常，这些位点聚集在转录本的某些区域，为其功能提供线索。因此，总结这些位点在转录本中的位置是很有意义的。元基因是一种用于可视化沿着简化转录本模型的位点分布的简单有效工具。在这项工作中，我们介绍了MetaPlotR，一个用于创建元基因图的Perl/R管道。
代码及相关教程可在https://github.com/olarerin/metaPlotR获取。
