Nagpal Madhav, Singh Shreya, Singh Pranshu, Chauhan Pallavi, Zaidi Meesam Abbas
Department of Oral Medicine and Radiology, SGT, Gurgaon, Haryana, India.
Department of Oral and Maxillofacial Pathology and Microbiology, Uttaranchal Dental and Medical Research Institute, Dehradun, Uttarakhand, India.
Natl J Maxillofac Surg. 2016 Jan-Jun;7(1):17-20. doi: 10.4103/0975-5950.196135.
The purpose of this review is to give a brief background to enable the judicious use of widely performed serum cancer markers. The markers could be product of cancerous cell or as response to cancer. They are usually proteins, which are mainly found in blood or urine. These markers may be employed to predict primary or secondary tumor risk. Sometimes, non-cancerous conditions can also cause elevation of some tumor markers to be higher than normal. Besides, not every cancer patient may have raised level of a tumor marker. For these reasons, knowledge about cancer biomarkers has increased tremendously. Awareness for cancer and related tumor markers providing great opportunities for improving the management of cancer patients by enhancing the efficiency of detection and efficacy of treatment.
本综述的目的是提供简要背景知识,以便明智地使用广泛应用的血清肿瘤标志物。这些标志物可能是癌细胞的产物,或者是对癌症的反应。它们通常是蛋白质,主要存在于血液或尿液中。这些标志物可用于预测原发性或继发性肿瘤风险。有时,非癌症疾病也会导致某些肿瘤标志物水平升高至高于正常水平。此外,并非每个癌症患者的肿瘤标志物水平都会升高。由于这些原因,关于癌症生物标志物的知识有了极大的增长。对癌症及相关肿瘤标志物的认识为通过提高检测效率和治疗效果来改善癌症患者的管理提供了巨大机遇。