Rajguru Jagadish Prasad, Mouneshkumar C D, Radhakrishnan Indu Cherangapadath, Negi Bhupender Singh, Maya Deepthi, Hajibabaei Sahar, Rana Vivek
Department of Oral and Maxillofacial Pathology, Hi-Tech Dental College and Hospital, Bhubaneswar, Odisha, India.
Department of Oral and Maxillofacial Surgery, School of Dental Sciences, Krishna Institute of Medical Sciences, Deemed to be University, Karad, Maharashtra, India.
J Family Med Prim Care. 2020 Feb 28;9(2):492-496. doi: 10.4103/jfmpc.jfmpc_1036_19. eCollection 2020 Feb.
Tumor markers are the substances produced in response to the presence of cancer either by the body itself or by the cancer cells. These markers mostly are the proteins that are produced at a greater rate by the cancer cells. Increased levels of these substances can be detected in urine, blood, or body tissues of the patients with certain types of cancer. These markers are useful in differentiating primary or secondary tumors. In few noncancerous conditions, these markers are often found to be elevated. For these reasons, the knowledge regarding these biomarkers has increased tremendously. This article classifies the different types of tumor markers and implicates their role in some diseases.
肿瘤标志物是机体自身或癌细胞针对癌症的存在而产生的物质。这些标志物大多是癌细胞以更高速率产生的蛋白质。在某些类型癌症患者的尿液、血液或身体组织中可检测到这些物质水平升高。这些标志物有助于鉴别原发性或继发性肿瘤。在少数非癌性疾病中,也常发现这些标志物升高。基于这些原因,关于这些生物标志物的知识有了极大增长。本文对不同类型的肿瘤标志物进行了分类,并阐述了它们在某些疾病中的作用。