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一名免疫功能正常的儿童出现胸腔积液,诊断为原发性肺外耐多药结核病。

Primary extrapulmonary multidrug-resistant tuberculosis in an immunocompetent child presenting with pleural effusion.

作者信息

Yadav Sankalp, Rawal Gautam

机构信息

General Duty Medical Officer-II, Department of Medicine & TB, Chest Clinic Moti Nagar, North Delhi Municipal Corporation, New Delhi, India.

Attending Consultant, Respiratory Intensive Care, Max Super Specialty Hospital, Saket, New Delhi, India.

出版信息

Transl Pediatr. 2017 Jan;6(1):72-75. doi: 10.21037/tp.2016.07.01.

DOI:10.21037/tp.2016.07.01
PMID:28164036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5253261/
Abstract

The developing countries are having a number of public health issues. The situation in these resource-limited countries is scary due to the huge burden of infectious diseases like tuberculosis (TB). The latest reports from the WHO shows a high number of drug resistant cases even in the pediatric age groups. Also, the lack of suspicion of drug resistant TB (DR-TB) in the pediatric cases, especially in the absence of a past or family history may lead to delay in diagnosis and flaring-up of the disease. We herein present the very first case of the primary multidrug-resistant TB in an HIV negative child who presented with the left sided pleural effusion.

摘要

发展中国家面临着诸多公共卫生问题。由于结核病等传染病的巨大负担,这些资源有限国家的情况令人担忧。世界卫生组织的最新报告显示,即使在儿童年龄组中,耐药病例数量也很高。此外,在儿科病例中,尤其是在没有既往或家族病史的情况下,对耐药结核病(DR-TB)缺乏怀疑可能导致诊断延迟和疾病爆发。我们在此报告首例原发性耐多药结核病病例,该病例为一名HIV阴性儿童,表现为左侧胸腔积液。

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本文引用的文献

1
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J Clin Diagn Res. 2016 Jan;10(1):RD01-3. doi: 10.7860/JCDR/2016/15395.7096. Epub 2016 Jan 1.
2
Tubercular Nodular Episcleritis: A Case Report.结核性结节性巩膜炎:一例报告
J Clin Diagn Res. 2015 Aug;9(8):ND01-2. doi: 10.7860/JCDR/2015/15023.6335. Epub 2015 Aug 1.
3
Clinical peculiarities of tuberculosis.结核病的临床特点。
BMC Infect Dis. 2014;14 Suppl 1(Suppl 1):S4. doi: 10.1186/1471-2334-14-S1-S4. Epub 2014 Jan 8.
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Primary disseminated extrapulmonary multidrug resistant tuberculosis.原发性播散性肺外多药耐药结核病
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Multidrug-resistant tuberculosis of the spine--is it the beginning of the end? A study of twenty-five culture proven multidrug-resistant tuberculosis spine patients.脊柱耐多药结核病——是否意味着终结的开始?对 25 例培养证实的耐多药结核脊柱患者的研究。
Spine (Phila Pa 1976). 2009 Oct 15;34(22):E806-10. doi: 10.1097/BRS.0b013e3181af7797.
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Pediatr Infect Dis J. 2006 Feb;25(2):147-50. doi: 10.1097/01.inf.0000199314.88063.4c.
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Familial outbreak of disseminated multidrug-resistant tuberculosis and meningitis.播散性耐多药结核病和脑膜炎的家族性暴发。
Int J Tuberc Lung Dis. 2001 Jun;5(6):551-8.
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Multidrug-resistant tuberculosis meningitis: clinical problems and concentrations of second-line antituberculous medications.耐多药结核性脑膜炎:临床问题及二线抗结核药物浓度
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