Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.
Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China.
Sci Rep. 2017 Feb 6;7:42067. doi: 10.1038/srep42067.
This study aims to determine the agreement of patient-measured intraocular pressure (IOP) using rebound tonometry with ophthalmologist-measured IOP using Goldmann applanation tonometry (GAT). Fifty-three glaucoma patients used rebound tonometry (Icare ONE, Icare Finland Oy., Finland) to measure their own IOP in ambient environments for 1 week, 5 times per day. Clinic IOP measurements were performed by ophthalmologists using GAT and by patients using rebound tonometry on examination days 1, 4 and 7 of the same week. The agreement between the two tonometries was evaluated by modified Bland-Altman plots and intra-class correlation coefficient (ICC) was determined. Differences in ICCs of them among the three examination days were evaluated by bootstrap resampling analysis. Respective within-measurement ICC of GAT and rebound tonometry were 0.98 and 0.94 on Day 1, 0.98 and 0.93 on Day 4, and 0.96 and 0.92 on Day 7. In a modified Bland-Altman plot, the mean difference ±1 standard deviation (SD) between the two tonometries was 0.15 ± 0.65 mmHg (p = 0.682). Between-measurement ICC were 0.66, 0.76 and 0.73 on the 3 examination days. There was no significant difference among ICCs. In conclusion, patient-measured IOP using rebound tonometry and ophthalmologist-measured IOP using GAT demonstrate good agreement.
本研究旨在确定使用回弹眼压计(Rebound tonometry)测量的患者眼压(IOP)与使用 Goldmann 压平眼压计(Goldmann applanation tonometry,GAT)测量的眼科医生眼压之间的一致性。53 名青光眼患者在一周内的日常环境中,每天使用回弹眼压计(Icare ONE,Icare Finland Oy.,芬兰)测量 5 次眼压。在同一周的第 1、4 和 7 天,由眼科医生使用 GAT 以及患者使用回弹眼压计进行临床眼压测量。通过改良的 Bland-Altman 图和组内相关系数(intra-class correlation coefficient,ICC)评估两种眼压计之间的一致性,并通过 bootstrap 重采样分析评估它们在 3 个检查日之间的 ICC 差异。在第 1 天、第 4 天和第 7 天,GAT 和回弹眼压计的各自内测量 ICC 分别为 0.98 和 0.94、0.98 和 0.93 以及 0.96 和 0.92。在改良的 Bland-Altman 图中,两种眼压计之间的平均差值±1 标准差(standard deviation,SD)为 0.15±0.65mmHg(p=0.682)。在 3 个检查日之间,组间 ICC 分别为 0.66、0.76 和 0.73。ICC 之间没有显著差异。总之,使用回弹眼压计测量的患者眼压与使用 GAT 测量的眼科医生眼压之间具有良好的一致性。