Taplin S, Anderman C, Grothaus L
Preventive Care Research, Center for Health Studies, Seattle, WA 98121.
Am J Public Health. 1989 Nov;79(11):1494-8. doi: 10.2105/ajph.79.11.1494.
Within the context of an organized breast cancer screening program we conducted a prospective evaluation of the relation between breast cancer risk and participation in mammographic screening. The influence on participation of known breast cancer risk factors, as well as a summary risk label, (i.e. "high", or "moderate") were examined. The overall participation rate was 71 percent among 2,422 women, 50 to 79 years of age, invited to a centralized clinic. Multivariate analyses showed participation to be somewhat decreased among women with late menopause and definitely increased among women with any of the following factors: 1) increased age; 2) a family history of breast cancer; and 3) a previous breast biopsy. Women in the high-risk group were most likely to participate but the effect of the label was stronger among women ages 50 to 59 compared to women ages 60 to 79. The study results are generally consistent with previous findings that participants in screening programs have higher rates of breast cancer. The results also suggest the possibility that providing breast cancer risk information may encourage participation in screening.
在一项有组织的乳腺癌筛查项目背景下，我们对乳腺癌风险与参与乳腺钼靶筛查之间的关系进行了前瞻性评估。研究了已知乳腺癌风险因素以及一个综合风险标签（即“高”或“中”）对参与筛查的影响。在受邀前往一家集中诊所的2422名年龄在50至79岁的女性中，总体参与率为71%。多变量分析显示，绝经较晚的女性参与率有所下降，而具有以下任何一种因素的女性参与率则明显增加：1）年龄增加；2）乳腺癌家族史；3）既往乳腺活检史。高风险组的女性最有可能参与筛查，但与60至79岁的女性相比，该标签对50至59岁女性的影响更强。研究结果总体上与之前的发现一致，即筛查项目的参与者患乳腺癌的比例更高。结果还表明，提供乳腺癌风险信息可能会鼓励参与筛查。
