Lee Jin Young, Sim Woo Seog, Kim Eun Sung, Lee Sangmin M, Kim Duk Kyung, Na Yu Ri, Park Dahye, Park Hue Jung
1 Department of Anaesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
2 Department of Anaesthesiology and Pain Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Int Med Res. 2017 Apr;45(2):744-752. doi: 10.1177/0300060516687227. Epub 2017 Feb 7.
Objective To investigate the incidence of postoperative sore throat (POST) in Korean patients undergoing general anaesthesia with endotracheal intubation and to assess potential risk factors. Methods This prospective study enrolled patients who underwent all types of elective surgical procedures with endotracheal intubation and general anaesthesia. The patients were categorized into group S (those with a POST) or group N (those without a POST). The demographic, clinical and anaesthetic characteristics of each group were compared. Results This study enrolled 207 patients and the overall incidence of POST was 57.5% ( n = 119). Univariate analysis revealed that significantly more patients in group S had a cough at emergence and hoarseness in the postanaesthetic care unit compared with group N. Receiver operating characteristic curve analysis showed that an intracuff pressure ≥17 cmHO was associated with POST. Multivariate analysis identified an intracuff pressure ≥17 cmHO and cough at emergence as risk factors for POST. At emergence, as the intracuff pressure over ≥17 cmHO increased, the incidence of hoarseness increased. Conclusions An intracuff pressure ≥17 cmHO and a cough at emergence were risk factors for POST in Korean patients. Intracuff monitoring during anaesthesia and a smooth emergence are needed to prevent POST.
目的 调查韩国接受气管插管全身麻醉患者术后咽痛(POST)的发生率,并评估潜在危险因素。方法 这项前瞻性研究纳入了接受各类择期手术且行气管插管全身麻醉的患者。患者被分为S组(有POST者)或N组(无POST者)。比较两组的人口统计学、临床和麻醉特征。结果 本研究纳入207例患者,POST的总体发生率为57.5%(n = 119)。单因素分析显示,与N组相比,S组中术后苏醒期咳嗽及在麻醉后护理单元出现声音嘶哑的患者明显更多。受试者工作特征曲线分析表明,套囊内压力≥17 cmH₂O与POST相关。多因素分析确定套囊内压力≥17 cmH₂O及术后苏醒期咳嗽为POST的危险因素。术后苏醒期,随着套囊内压力≥17 cmH₂O的升高,声音嘶哑的发生率增加。结论 套囊内压力≥17 cmH₂O及术后苏醒期咳嗽是韩国患者发生POST的危险因素。麻醉期间需要进行套囊内压力监测并实现平稳苏醒以预防POST。