Zorn T M, Bijovsky A T, Bevilacqua E M, Abrahamsohn P A
Department of Histology and Embryology, University of São Paulo, Brazil.
Anat Rec. 1989 Oct;225(2):96-100. doi: 10.1002/ar.1092250203.
Collagen fibrils were present within membrane-bound vacuoles in the cytoplasm of mouse decidual cells on the 7th day of pregnancy. The space between the vacuole membranes and the fibrils was narrow and frequently filled with a granular electron-dense material. The loss of banding of the collagen fibrils, their association with lysosomelike bodies, and the demonstration of acid phosphatase activity in the vacuoles indicate that the fibrils were internalized by the decidual cells and were being digested. It is suggested that phagocytosis of collagen is a mechanism of remodeling of the mouse decidua.
妊娠第7天，小鼠蜕膜细胞的细胞质中，膜结合空泡内存在胶原纤维。空泡膜与纤维之间的间隙狭窄，且常充满颗粒状电子致密物质。胶原纤维条纹的消失、它们与溶酶体样小体的关联以及空泡中酸性磷酸酶活性的证明表明，这些纤维被蜕膜细胞内化并正在被消化。有人提出，胶原的吞噬作用是小鼠蜕膜重塑的一种机制。
