Xia Lisheng, Gu Ruolei, Zhang Dandan, Luo Yuejia
College of Information Engineering, Shenzhen University Shenzhen, China.
Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences Beijing, China.
Front Behav Neurosci. 2017 Jan 24;11:5. doi: 10.3389/fnbeh.2017.00005. eCollection 2017.
Impulsivity, which is linked to a wide range of psychiatric disorders, is often characterized by a preference for immediate but smaller rewards over delayed but larger rewards. However, debate exists on the relationship between anxiety and impulsivity. Here we use event-related potential (ERP) components as biomarkers in the temporal discounting task to examine the effect of anxiety on inter-temporal decision-making. Our behavioral results indicated that the high trait anxiety (HTA) group made significantly more immediate choices than the low trait anxiety (LTA) group. Compared with the LTA group, shorter response time was associated with immediate rewards in the HTA group. Furthermore, previous studies have demonstrated three ERP components that are associated with impulsivity and/or delay discounting. First, the N1 is an early sensory component involved in selective attention and attention processing for goal-directed actions. Second, the reward positivity (RewP) reflects reward-related dopaminergic activity and encodes reward values. Third, the P3 is regarded as a measure of motivational significance in the decision-making literature. Accordingly, this study found in the immediate-option-evoked ERPs that the HTA group had a larger N1 than the LTA group did. For the delayed-option-evoked ERPs, the HTA group had larger N1 and RewP for the immediate choice than the LTA group did, while the LTA group had a larger P3 for the delayed choice than the HTA group did. These results support the notion that anxiety individuals are impulsive decision-makers in the Delay Discounting Task.
冲动性与多种精神疾病相关,其特征通常是相较于延迟但更大的奖励,更倾向于即时但较小的奖励。然而,关于焦虑与冲动性之间的关系存在争议。在此,我们使用事件相关电位(ERP)成分作为时间折扣任务中的生物标志物,以研究焦虑对跨期决策的影响。我们的行为结果表明,高特质焦虑(HTA)组比低特质焦虑(LTA)组做出即时选择的次数显著更多。与LTA组相比,HTA组中即时奖励与更短的反应时间相关。此外,先前的研究已经证明了三个与冲动性和/或延迟折扣相关的ERP成分。首先,N1是一个早期感觉成分,参与选择性注意和对目标导向行为的注意加工。其次,奖励正波(RewP)反映与奖励相关的多巴胺能活动并编码奖励价值。第三,P3在决策文献中被视为动机显著性的一种度量。因此,本研究在即时选项诱发的ERP中发现,HTA组的N1比LTA组更大。对于延迟选项诱发的ERP,HTA组在即时选择时的N1和RewP比LTA组更大,而LTA组在延迟选择时的P3比HTA组更大。这些结果支持了这样一种观点,即焦虑个体在延迟折扣任务中是冲动的决策者。
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