Cavalcanti Marta G, Cabral-Castro Mauro J, Gonçalves Jorge L S, Santana Larissa S, Pimenta Eduardo Scarlatelli, Peralta José M
Serviço de Doenças Infecciosas e Parasitárias, Hospital Clementino Fraga Filho, Universidade Federal do Rio de Janeiro (HUCFF/UFRJ), Rio de Janeiro, Brazil; Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (IMPG/UFRJ), Rio de Janeiro, Brazil.
Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (IMPG/UFRJ), Rio de Janeiro, Brazil.
Int J Infect Dis. 2017 Apr;57:70-72. doi: 10.1016/j.ijid.2017.01.042. Epub 2017 Feb 8.
Zika virus (ZIKV) transmission through non-mosquito-dependent routes has become increasingly important since reports of sexual transmission. Breastfeeding is a potential means of ZIKV transmission, but data on this remain limited. The cases of four mothers with laboratory-proven infections are reported. No disease evolved in three of the breastfed babies despite detectable maternal viremia and viruria, the presence of viral RNA shedding, and the isolation of infective particles in one milk sample. Fever and rash in one infant of a ZIKV-infected mother proved to be related to chikungunya virus infection. The results suggest that the presence of infective particles in breast milk may not be sufficient for the efficient perinatal transmission of ZIKV.
自出现性传播的报道以来，寨卡病毒（ZIKV）通过非蚊虫依赖途径传播变得愈发重要。母乳喂养是寨卡病毒传播的一种潜在途径，但相关数据仍然有限。本文报告了4例经实验室确诊感染的母亲。尽管母亲存在可检测到的病毒血症和病毒尿、病毒RNA脱落，且在一份乳汁样本中分离出感染性颗粒，但3名母乳喂养婴儿均未发病。一名感染寨卡病毒母亲的婴儿出现发热和皮疹，后来证实与基孔肯雅病毒感染有关。结果表明，母乳中存在感染性颗粒可能不足以实现寨卡病毒的有效围产期传播。
