Piikivi L, Tolonen U
Oulu Health Centre, Division of Occupational Health, Finland.
Br J Ind Med. 1989 Jun;46(6):370-5. doi: 10.1136/oem.46.6.370.
The cerebral effect of long term (mean 15.6, SD 8.9 years) and low (about 25 micrograms/m3 air) exposure to mercury vapour was studied in a group of 41 workers in a chlor-alkali plant and in a group of matched referents by electroencephalography (EEG). In the visually interpreted EEGs only a tendency for an increased number of EEG abnormalities, especially focal ones, could be seen in the exposed subjects. In the computerised EEG (cEEG), however, the exposed workers had significantly slower and more attenuated EEGs than the referants. This difference was most prominent in the occipital region, became milder parietally, and was almost absent frontally. Our results suggest that cEEG may show early effects on the brain of exposure to mercury vapour.
通过脑电图(EEG)对一组氯碱厂的41名工人以及一组匹配的对照对象进行了研究,以探讨长期(平均15.6年,标准差8.9年)低剂量(空气中约25微克/立方米)汞蒸气暴露对大脑的影响。在视觉解读的脑电图中,仅在暴露组中可见脑电图异常数量增加的趋势,尤其是局灶性异常。然而,在计算机化脑电图(cEEG)中,暴露工人的脑电图明显比对照组更慢且衰减更明显。这种差异在枕叶区域最为显著,在顶叶区域变轻,而在前额叶区域几乎不存在。我们的结果表明,cEEG可能显示出汞蒸气暴露对大脑的早期影响。