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采用开放式骨膜转移技术保存牙槽嵴用于骨量不足牙槽窝的随机对照临床试验。

Alveolar ridge preservation using an open membrane approach for sockets with bone deficiency: A randomized controlled clinical trial.

机构信息

Department of Periodontology, Veterans Health Service Medical Center, Seoul, Republic of Korea.

Department of Periodontology, School of Dentistry, Kyung Hee University, Seoul, Republic of Korea.

出版信息

Clin Implant Dent Relat Res. 2019 Feb;21(1):175-182. doi: 10.1111/cid.12668. Epub 2018 Nov 5.

DOI:10.1111/cid.12668
PMID:30394672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6587521/
Abstract

BACKGROUND

Various approaches are used for alveolar ridge preservation (ARP); however, there is no standard method or material.

PURPOSE

To investigate the effect of ARP with a dense polytetrafluoroethylene (d-PTFE) membrane and freeze-dried irradiated allogenic bone for sockets with bone deficiency.

MATERIALS AND METHODS

Thirty-four patients (with sockets exhibiting ≥3 mm hard tissue loss in ≥1 walls) were randomized to undergo natural socket healing (control) or ARP with a d-PTFE membrane and freeze-dried irradiated allogenic bone (test group). After 4 months, horizontal and vertical ridge changes were measured using cone beam computed tomography.

RESULTS

Ridge width at l mm below the ridge crest demonstrated significantly less change in the test group (median =2.3; Q1 = 0.6; Q3 = 4.3 mm) than in the control group (median =3.9; Q1 =2.6; Q3 = 7.8 mm; P = .021). There was no significant difference between the two groups in horizontal ridge changes at 3 and 5 mm below the crest or vertical changes (P > .05). Requirement for bone augmentation at implant placement was significantly reduced in the test group compared to the control group (P < .001).

CONCLUSION

ARP with a d-PTFE membrane and freeze-dried irradiated allogenic bone substitute reduced horizontal bone resorption in sockets with bone deficiency.

摘要

背景

各种方法被用于牙槽嵴保存(ARP);然而,目前还没有标准的方法或材料。

目的

研究使用致密聚四氟乙烯(d-PTFE)膜和冻干辐照同种异体骨对骨量不足的牙槽窝进行 ARP 的效果。

材料与方法

34 名患者(牙槽窝在至少 1 个壁上有≥3mm 的硬组织丧失)被随机分为自然牙槽窝愈合组(对照组)或使用 d-PTFE 膜和冻干辐照同种异体骨的 ARP 组(实验组)。4 个月后,使用锥形束 CT 测量水平和垂直牙槽嵴变化。

结果

在牙槽嵴顶下 1mm 处的牙槽嵴宽度,实验组的变化明显小于对照组(中位数=2.3;Q1=0.6;Q3=4.3mm)(中位数=3.9;Q1=2.6;Q3=7.8mm;P=0.021)。在牙槽嵴顶下 3mm 和 5mm 处的水平牙槽嵴变化或垂直变化方面,两组间无显著差异(P>.05)。与对照组相比,实验组在种植体植入时对骨增量的需求显著降低(P<.001)。

结论

使用 d-PTFE 膜和冻干辐照同种异体骨替代物进行 ARP 可减少骨量不足牙槽窝的水平骨吸收。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/eb0b3f1f9eea/CID-21-175-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/84dc1413967e/CID-21-175-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/33772b1149db/CID-21-175-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/4dd0d702ade8/CID-21-175-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/b89d5685830b/CID-21-175-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/eb0b3f1f9eea/CID-21-175-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/84dc1413967e/CID-21-175-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/33772b1149db/CID-21-175-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/4dd0d702ade8/CID-21-175-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/b89d5685830b/CID-21-175-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b43/6587521/eb0b3f1f9eea/CID-21-175-g005.jpg

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