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粪便微生物群移植：在根除耐碳青霉烯类肺炎克雷伯菌肠道定植方面是否发挥作用？

Fecal microbiota transplantation: is there a role in the eradication of carbapenem-resistant Klebsiella pneumoniae intestinal carriage?

作者信息

Ponte Ana, Pinho Rolando, Mota Margarida

机构信息

Gastrenterologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal.

Gastroenterology and Hepatology department, Centro Hospitalar de Gaia/Espinho, Portugal.

出版信息

Rev Esp Enferm Dig. 2017 May;109(5):392. doi: 10.17235/reed.2017.4425/2016.

DOI:10.17235/reed.2017.4425/2016
PMID:28196423
Abstract

The authors present the case of a 66-year-old woman with four hospitalizations due to recurrent Clostridium difficile infection (CDI) non responsive to vancomycin and fidaxomicin. Furthermore, intestinal colonization with carbapenem-resistant Klebsiella pneumoniae (CRKP) was identified after a positive stool culture in a screening routinely performed in our center in patients recently hospitalized.

摘要

作者报告了一例66岁女性患者的病例，该患者因复发性艰难梭菌感染（CDI）住院四次，对万古霉素和非达霉素均无反应。此外，在我们中心对近期住院患者常规进行的筛查中，粪便培养呈阳性后，发现该患者肠道定植了耐碳青霉烯类肺炎克雷伯菌（CRKP）。

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Fecal microbiota transplantation: is there a role in the eradication of carbapenem-resistant Klebsiella pneumoniae intestinal carriage?粪便微生物群移植：在根除耐碳青霉烯类肺炎克雷伯菌肠道定植方面是否发挥作用？
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Infect Drug Resist. 2022 Oct 31;15:6287-6295. doi: 10.2147/IDR.S386309. eCollection 2022.
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The potential utility of fecal (or intestinal) microbiota transplantation in controlling infectious diseases.粪便（或肠道）微生物群移植在控制传染病中的潜在应用。
Gut Microbes. 2022 Jan-Dec;14(1):2038856. doi: 10.1080/19490976.2022.2038856.
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The Intestinal Microbiota as a Reservoir and a Therapeutic Target to Fight Multi-Drug-Resistant Bacteria: A Narrative Review of the Literature.
肠道微生物群作为对抗多重耐药菌的储存库和治疗靶点：文献综述
Infect Dis Ther. 2019 Dec;8(4):469-482. doi: 10.1007/s40121-019-00272-7. Epub 2019 Oct 25.
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