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field recordings effectively monitor the mouse cortex and hippocampus under isoflurane anesthesia.

作者信息

Yin Yi-Qing, Wang Li-Fang, Chen Chao, Gao Teng, Zhao Zi-Fang, Li Cheng-Hui

机构信息

Department of Anesthesiology, China-Japan Friendship Hospital, Beijing, China.

出版信息

Neural Regen Res. 2016 Dec;11(12):1951-1955. doi: 10.4103/1673-5374.197136.

DOI:10.4103/1673-5374.197136
PMID:28197191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5270433/
Abstract

Isoflurane is a widely used inhaled anesthetic in the clinical setting. However, the mechanism underlying its effect on consciousness is under discussion. Therefore, we investigated the effect of isoflurane on the hippocampus and cortex using an field recording approach. Our results showed that 1.3%, 0.8%, and 0.4% isoflurane exerted an inhibitory influence on the mouse hippocampus and cortex. Further, high frequency bands in the cortex and hippocampus showed greater suppression with increasing isoflurane concentration. Our findings suggest that field recordings can monitor the effect of isoflurane anesthesia on the mouse cortex and hippocampus.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/539c7b11ad51/NRR-11-1951-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/1251a7bd5668/NRR-11-1951-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/d105e8cf4f26/NRR-11-1951-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/539c7b11ad51/NRR-11-1951-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/1251a7bd5668/NRR-11-1951-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/d105e8cf4f26/NRR-11-1951-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1112/5270433/539c7b11ad51/NRR-11-1951-g005.jpg

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