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直视下内尿道切开术治疗孤立性尿道成形术后狭窄:一项回顾性分析

Direct visual internal urethrotomy for isolated, post-urethroplasty strictures: a retrospective analysis.

作者信息

Brown Elizabeth Timbrook, Mock Stephen, Dmochowski Roger, Reynolds W Stuart, Milam Douglas, Kaufman Melissa R

机构信息

Vanderbilt University Medical Center, A1302 Medical Center North, Nashville, TN 37232-2102, USA.

Vanderbilt University Medical Center, Nashville, TN, USA.

出版信息

Ther Adv Urol. 2017 Feb;9(2):39-44. doi: 10.1177/1756287216679946. Epub 2016 Dec 2.

Abstract

BACKGROUND

Urethroplasty is often successful for the treatment of male urethral stricture disease, but limited data exists on recurrence management. Our goal was to evaluate direct visual internal urethrotomy (DVIU) as a treatment option for isolated, recurrent strictures after urethroplasty.

METHODS

We retrospectively identified male patients who underwent urethroplasty from 1999 to 2013 and developed an isolated, recurrent stricture at the urethroplasty site treated with DVIU. Success was defined as lack of symptomatology and no subsequent intervention. Comparative analysis identified characteristics and stricture properties associated with success.

RESULTS

A total of 436 urethroplasties were performed in 401 patients at our institution between 1999 and 2013. Stricture recurrence was noted in 64 (16%) patients. Of these, 47 (73%) underwent a DVIU. A total of 37 patients met inclusion criteria and underwent 50 DVIU procedures at the urethroplasty site. A single DVIU was successful in 13 of 37 patients (35%). A total of 4 of 6 patients required a second DVIU (67%). Overall, 17 of 43 (40%) of the total DVIUs were successful after urethroplasty. Success did not differ by age, stricture length or location, surgical technique, radiation history, prior urethroplasty or DVIU, time to failure, or etiology.

CONCLUSIONS

Post-urethroplasty DVIU for isolated, recurrent strictures may be offered as a minimally invasive treatment option. Approximately 40% of patients were spared further intervention.

摘要

背景

尿道成形术通常能成功治疗男性尿道狭窄疾病,但关于复发管理的数据有限。我们的目标是评估直视下内部尿道切开术(DVIU)作为尿道成形术后孤立性复发性狭窄的一种治疗选择。

方法

我们回顾性地确定了1999年至2013年间接受尿道成形术并在尿道成形术部位出现孤立性复发性狭窄且接受DVIU治疗的男性患者。成功定义为无症状且无需后续干预。比较分析确定了与成功相关的特征和狭窄特性。

结果

1999年至2013年间,我们机构对401例患者进行了436次尿道成形术。64例(16%)患者出现狭窄复发。其中,47例(73%)接受了DVIU。共有37例患者符合纳入标准,并在尿道成形术部位接受了50次DVIU手术。单次DVIU在37例患者中的13例(35%)成功。6例患者中有4例(67%)需要进行第二次DVIU。总体而言,43次DVIU中的17次(40%)在尿道成形术后成功。成功与否在年龄、狭窄长度或位置、手术技术、放疗史、既往尿道成形术或DVIU、失败时间或病因方面无差异。

结论

对于孤立性复发性狭窄,尿道成形术后的DVIU可作为一种微创治疗选择。约40%的患者无需进一步干预。

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