重症患儿脑脊液中的锰和硒浓度。
Manganese and selenium concentrations in cerebrospinal fluid of seriously ill children.
作者信息
Franěk Tomáš, Kotaška Karel, Průša Richard
机构信息
Department of Medical Chemistry and Clinical Biochemistry 2nd Faculty of Medicine, Faculty Hospital Motol, Charles University, Prague, Czech Republic.
出版信息
J Clin Lab Anal. 2017 Nov;31(6). doi: 10.1002/jcla.22122. Epub 2017 Feb 15.
BACKGROUND
The homeostasis of essential trace elements such as selenium and manganese may be altered in patients with severe diseases of various etiologies (trauma brain injuries, tumors, leukemias, lymphomas, neurological diseases).
METHODS
Concentration of manganese and selenium were determined in cerebrospinal fluid by electrothermal atomic absorption spectrometry in 50 hospitalized children with various clinical ethiologies including oncological, neurological, and brain related diseases.
RESULTS
The concentrations of manganese in cerebrospinal fluid of children were 0.97±0.67 μg/L. The concentrations of selenium were 13.3±3.5 μg/L. The concentrations were similar as published in adults. The values did not correlated with the age, gender and severity of the disease.
CONCLUSION
We evaluated values of selenium and manganese in cerebrospinal fluid of seriously diseased children.
背景
在患有各种病因（创伤性脑损伤、肿瘤、白血病、淋巴瘤、神经疾病）的重症患者中，硒和锰等必需微量元素的稳态可能会发生改变。
方法
采用电热原子吸收光谱法测定了50例患有包括肿瘤、神经和脑相关疾病等各种临床病因的住院儿童脑脊液中锰和硒的浓度。
结果
儿童脑脊液中锰的浓度为0.97±0.67μg/L。硒的浓度为13.3±3.5μg/L。这些浓度与已发表的成人数据相似。这些值与疾病的年龄、性别和严重程度无关。
结论
我们评估了重症患病儿童脑脊液中硒和锰的值。
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