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鉴定由P/C mRNA编码的一种额外的仙台病毒非结构蛋白。

Identification of an additional Sendai virus non-structural protein encoded by the P/C mRNA.

作者信息

Curran J A, Kolakofsky D

机构信息

Department of Microbiology, University of Geneva Medical School, Switzerland.

出版信息

J Gen Virol. 1987 Sep;68 ( Pt 9):2515-9. doi: 10.1099/0022-1317-68-9-2515.

Abstract

Peptide antiserum and monoclonal antibodies have detected a previously unrecognized small non-structural protein in Sendai virus-infected cells. This protein, designated X, appears to represent the C-terminal 95 amino acids of the P protein reading frame. The X protein appears to be almost as abundant as the P protein on a molar basis in vivo. No evidence of a precursor-product relationship between the X and P proteins could be found.

摘要

肽抗血清和单克隆抗体在仙台病毒感染的细胞中检测到一种以前未被识别的小非结构蛋白。这种蛋白被命名为X,似乎代表P蛋白阅读框的C末端95个氨基酸。在体内,按摩尔计算,X蛋白的丰度似乎几乎与P蛋白一样高。未发现X蛋白和P蛋白之间存在前体-产物关系的证据。

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