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本文引用的文献

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Enhancing bowel preparation instructions: Is the bang worth the buck, or are we stuck with the muck?
Gastrointest Endosc. 2017 Jan;85(1):98-100. doi: 10.1016/j.gie.2016.06.039.
2
Effectiveness of Screening Colonoscopy to Prevent Colorectal Cancer Among Medicare Beneficiaries Aged 70 to 79 Years: A Prospective Observational Study.70至79岁医疗保险受益人群中结肠镜筛查预防结直肠癌的有效性:一项前瞻性观察研究。
Ann Intern Med. 2017 Jan 3;166(1):18-26. doi: 10.7326/M16-0758. Epub 2016 Sep 27.
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Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement.结直肠癌筛查:美国预防服务工作组推荐声明。
JAMA. 2016 Jun 21;315(23):2564-2575. doi: 10.1001/jama.2016.5989.
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Enhanced instructions improve the quality of bowel preparation for colonoscopy: a meta-analysis of randomized controlled trials.增强指导可提高结肠镜检查的肠道准备质量:一项随机对照试验的荟萃分析。
Gastrointest Endosc. 2017 Jan;85(1):90-97.e6. doi: 10.1016/j.gie.2016.05.012. Epub 2016 May 14.
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Endoscopy in patients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines.抗血小板或抗凝治疗患者的内镜检查,包括直接口服抗凝剂:英国胃肠病学会(BSG)和欧洲胃肠内镜学会(ESGE)指南
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Validated Scales for Colon Cleansing: A Systematic Review.结肠清洁的验证量表:系统评价
Am J Gastroenterol. 2016 Feb;111(2):197-204; quiz 205. doi: 10.1038/ajg.2015.417. Epub 2016 Jan 19.
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The ageing gastrointestinal tract.衰老的胃肠道。
Curr Opin Clin Nutr Metab Care. 2016 Jan;19(1):12-8. doi: 10.1097/MCO.0000000000000238.
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Low-residue versus clear liquid diet before colonoscopy: a meta-analysis of randomized, controlled trials.结肠镜检查前低渣饮食与清流饮食对比:一项随机对照试验的荟萃分析
Gastrointest Endosc. 2016 Mar;83(3):499-507.e1. doi: 10.1016/j.gie.2015.09.045. Epub 2015 Oct 13.
9
Split-Dose Preparations Are Superior to Day-Before Bowel Cleansing Regimens: A Meta-analysis.分剂量制剂优于前一天肠道准备方案:一项荟萃分析。
Gastroenterology. 2015 Jul;149(1):79-88. doi: 10.1053/j.gastro.2015.04.004. Epub 2015 Apr 8.
10
Predicting inadequate bowel preparation for colonoscopy in participants receiving split-dose bowel preparation: development and validation of a prediction score.预测接受分次肠道准备的参与者结肠镜检查肠道准备不足:预测评分的制定和验证。
Gastrointest Endosc. 2015 Mar;81(3):665-72. doi: 10.1016/j.gie.2014.09.066. Epub 2015 Jan 17.

老年患者结肠镜检查的最佳肠道准备

Optimal Bowel Cleansing for Colonoscopy in the Elderly Patient.

作者信息

Ho Samuel B, Hovsepians Rita, Gupta Samir

机构信息

VA San Diego Healthcare System and University of California, 3350 La Jolla Village Drive, San Diego, CA, 92161, USA.

出版信息

Drugs Aging. 2017 Mar;34(3):163-172. doi: 10.1007/s40266-017-0436-z.

DOI:10.1007/s40266-017-0436-z
PMID:28214970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5374979/
Abstract

Colonoscopy is an important diagnostic and screening tool for colorectal cancer detection and prevention, and adequate bowel preparation is critical for successful colonoscopy. Complications related to colonoscopy, either directly or indirectly related to the procedure, are increased in elderly patients, and the risks and benefits of colonoscopy procedures need to be carefully considered in these patients. Recent studies have shown that 4 L polyethylene glycol with a split preparation is safe and effective for elderly patients, and is the preferred preparation for patients with medical comorbidities. Preparations containing sodium phosphate are generally not recommended for the elderly because of increased renal complications. In addition, a low-residue diet may aid in tolerance and willingness to undergo the procedure compared with a clear liquid diet, with comparable bowel preparation adequacy. Risk factors for inadequate bowel preparations include poor adherence to split preparation instructions or volume of solution ingested, and certain patient-related medications and comorbidities, such as diabetes, elevated body mass index, and antidepressant or narcotic use. Methods for achieving safe and adequate bowel preparations in the elderly include clear instructions, reminder calls, and case management for potential confounding patient-related factors.

摘要

结肠镜检查是结直肠癌检测和预防的重要诊断及筛查工具,充分的肠道准备对于结肠镜检查的成功至关重要。与结肠镜检查直接或间接相关的并发症在老年患者中有所增加,因此在这些患者中需要仔细考虑结肠镜检查的风险和益处。最近的研究表明,4升聚乙二醇分阶段服用对老年患者安全有效,是患有内科合并症患者的首选肠道准备方法。由于肾并发症增加,一般不建议老年患者使用含磷酸钠的肠道准备剂。此外,与清流食相比,低渣饮食可能有助于提高患者对结肠镜检查的耐受性和接受意愿,且肠道准备的充分程度相当。肠道准备不充分的风险因素包括未严格遵循分阶段服用说明或摄入溶液量不足,以及某些与患者相关的药物和合并症,如糖尿病、体重指数升高、使用抗抑郁药或麻醉药等。在老年患者中实现安全且充分的肠道准备的方法包括提供清晰的说明、提醒电话以及对潜在的与患者相关的混杂因素进行病例管理。