Pericardial Fluid Exosomes: A New Material to Treat Cardiovascular Disease.
作者信息
Sahoo Susmita, Mathiyalagan Prabhu, Hajjar Roger J
机构信息
Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
出版信息
Mol Ther. 2017 Mar 1;25(3):568-569. doi: 10.1016/j.ymthe.2017.02.002. Epub 2017 Feb 16.
Abstract
摘要
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Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis.人心包液含有富含心血管表达的微小RNA的外泌体，并促进治疗性血管生成。
Mol Ther. 2017 Mar 1;25(3):679-693. doi: 10.1016/j.ymthe.2016.12.022. Epub 2017 Feb 1.
2
Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction.心脏球来源细胞分泌的细胞外囊泡可减少疤痕形成、减弱不良重构、改善急性和慢性猪心肌梗死的功能。
Eur Heart J. 2017 Jan 14;38(3):201-211. doi: 10.1093/eurheartj/ehw240.
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Exosomes-Based Gene Therapy for MicroRNA Delivery.基于外泌体的微小RNA递送基因治疗
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