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减重分流术会导致骨密度降低,但能减轻考虑进行脊柱手术的病态肥胖患者的轴向背痛。

Bariatric bypasses contribute to loss of bone mineral density but reduce axial back pain in morbidly obese patients considering spine surgery.

作者信息

Epstein Nancy E

机构信息

Chief of Neurosurgical Spine and Education, Winthrop University Hospital, Mineola, New York, USA.

出版信息

Surg Neurol Int. 2017 Jan 19;8:13. doi: 10.4103/2152-7806.198740. eCollection 2017.

DOI:10.4103/2152-7806.198740
PMID:28217392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5288988/
Abstract

BACKGROUND

Many spine surgeons recommend stringent weight loss, including bariatric bypass procedures, prior to "elective" spine surgery (should not be for axial back pain alone) in morbidly obese patients (defined by a body mass index (BMI) of >40 mg/kg or >35 mg/kg with two or more major comorbidities) to reduce their greater risk for major perioperative complications. Although bypasses typically lead to marked weight reduction and even reduced axial back pain, they also promote unrecognized and often insufficiently treated vitamin D deficiency and loss of bone mineral density.

METHODS

Morbidly obese patients who are under consideration for "elective" spine operations (other than for back pain alone) are often told to lose weight. Some choose to undergo bariatric bypass procedures, but are unaware of the potential risks/complications of these procedures.

RESULTS

Within the first 2 years following most bariatric bypass procedures, patients experience not only marked loss of weight and muscle mass, but also significant vitamin D deficiency and loss of bone mineral density, increasing their susceptibility to fractures. Nevertheless, some patients also experience a sufficient reduction of axial back pain to avoid spinal surgery.

CONCLUSIONS

Morbidly obese patients under consideration for "elective" spine surgery may undergo bariatric bypass procedures that lead to a significant reduction of vitamin D levels and loss of bone mineral density. However, potential benefits may include a sufficient reduction of axial back pain to avoid surgery in a select subset of patients altogether.

摘要

背景

许多脊柱外科医生建议,对于病态肥胖患者(定义为体重指数(BMI)>40mg/kg或>35mg/kg且伴有两种或更多种主要合并症),在进行“择期”脊柱手术(不应仅针对轴性背痛)之前进行严格的体重减轻,包括减重手术,以降低其围手术期重大并发症的较高风险。尽管减重手术通常会导致显著的体重减轻,甚至轴性背痛减轻,但它们也会导致未被认识且往往治疗不足的维生素D缺乏和骨矿物质密度降低。

方法

正在考虑进行“择期”脊柱手术(而非仅针对背痛)的病态肥胖患者经常被告知要减肥。一些患者选择接受减重手术,但并未意识到这些手术的潜在风险/并发症。

结果

在大多数减重手术后的头2年内,患者不仅体重和肌肉量显著下降,还会出现明显的维生素D缺乏和骨矿物质密度降低,增加了骨折易感性。然而,一些患者的轴性背痛也有足够减轻,从而避免了脊柱手术。

结论

正在考虑进行“择期”脊柱手术的病态肥胖患者可能会接受减重手术,这会导致维生素D水平显著降低和骨矿物质密度下降。然而,潜在益处可能包括在一部分特定患者中轴性背痛充分减轻,从而完全避免手术。

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Calcif Tissue Int. 2016 Mar;98(3):253-62. doi: 10.1007/s00223-015-0091-5. Epub 2015 Dec 12.
2
Understanding the Impact of Obesity on Short-term Outcomes and In-hospital Costs After Instrumented Spinal Fusion.了解肥胖对脊柱内固定融合术后短期预后及住院费用的影响。
Neurosurgery. 2016 Jan;78(1):127-32. doi: 10.1227/NEU.0000000000001018.
3
The effects of laparoscopic sleeve gastrectomy on head, neck, shoulder, low back and knee pain of female patients.腹腔镜袖状胃切除术对女性患者头部、颈部、肩部、下背部和膝盖疼痛的影响。
Int J Clin Exp Med. 2015 Feb 15;8(2):2668-73. eCollection 2015.
4
Two-year changes in bone density after Roux-en-Y gastric bypass surgery.Roux-en-Y胃旁路手术后两年的骨密度变化。
J Clin Endocrinol Metab. 2015 Apr;100(4):1452-9. doi: 10.1210/jc.2014-4341. Epub 2015 Feb 3.
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