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连接组发育中的延迟稳定和个体化与精神障碍有关。

Delayed stabilization and individualization in connectome development are related to psychiatric disorders.

机构信息

NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital &Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Department of Psychology, University of Oslo, Oslo, Norway.

出版信息

Nat Neurosci. 2017 Apr;20(4):513-515. doi: 10.1038/nn.4511. Epub 2017 Feb 20.

Abstract

The brain functional connectome constitutes a unique fingerprint allowing identification of individuals among a pool of people. Here we establish that the connectome develops into a more stable, individual wiring pattern during adolescence and demonstrate that a delay in this network tuning process is associated with reduced mental health in the formative years of late neurodevelopment.

摘要

大脑功能连接组构成了一个独特的指纹,可以在人群中识别个体。在这里,我们证明连接组在青春期发展成一种更稳定、个体的连接模式,并表明这种网络调整过程的延迟与形成期后期神经发育过程中心理健康的下降有关。

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