2015年巴西巴伊亚州各市吉兰-巴雷综合征及其他可能与寨卡病毒感染相关的神经学表现
Guillain-Barré syndrome and other neurological manifestations possibly related to Zika virus infection in municipalities from Bahia, Brazil, 2015.
作者信息
Malta Juliane Maria Alves Siqueira, Vargas Alexander, Leite Priscila Leal E, Percio Jadher, Coelho Giovanini Evelim, Ferraro Andréa Helena Argolo, Cordeiro Tânia Maria de Oliveira, Dias Jesângeli de Sousa, Saad Eduardo
机构信息
Ministério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do Sistema Único de Saúde, Brasília-DF, Brasil.
Ministério da Saúde, Programa Nacional de Controle da Dengue, Brasília-DF, Brasil.
出版信息
Epidemiol Serv Saude. 2017 Jan-Mar;26(1):9-18. doi: 10.5123/S1679-49742017000100002.
OBJECTIVE
to describe the reported cases of Guillain-Barré Syndrome (GBS) and other neurological manifestations with a history of dengue, chikungunya or Zika virus infections, in the Metropolitan Region of Salvador and in the municipality of Feira de Santana, Brazil.
METHODS
this is a descriptive study with data of an investigation conducted by the epidemiological surveillance from March to August 2015; to confirm the neurological manifestations, medical diagnosis records were considered, and to prior infection, clinical and laboratory criteria were used.
RESULTS
138 individuals were investigated, 57 reported infectious process up to 31 days before neurological symptoms - 30 possibly due to Zika, 13 to dengue, 8 to chikungunya and 6 were inconclusive -; GBS was the most frequent neurological condition (n=46), with predominance of male sex (n=32) and the median age was 44.
CONCLUSION
most cases reported a clinical picture consistent with acute Zika virus disease, which preceded the occurrence of neurological symptoms.
目的
描述巴西萨尔瓦多都会区和费拉德桑塔纳市报告的有登革热、基孔肯雅热或寨卡病毒感染史的吉兰-巴雷综合征（GBS）及其他神经表现病例。
方法
这是一项描述性研究，采用了2015年3月至8月流行病学监测调查的数据；为确认神经表现，参考了医学诊断记录，对于既往感染，采用了临床和实验室标准。
结果
共调查了138人，57人报告在出现神经症状前31天内有感染过程——30人可能感染寨卡病毒，13人感染登革热，8人感染基孔肯雅热，6人情况不明——；GBS是最常见的神经疾病（n = 46），以男性为主（n = 32），中位年龄为44岁。
结论
大多数病例报告的临床表现与急性寨卡病毒病相符，且先于神经症状出现。
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