Collins Deirdre A, Putsathit Papanin, Elliott Briony, Riley Thomas V
Microbiology and Immunology, School of Pathology and Laboratory Medicine, the University of Western Australia, Perth, WA, Australia.
Microbiology and Immunology, School of Pathology and Laboratory Medicine, the University of Western Australia, Perth, WA, Australia.
Pathology. 2017 Apr;49(3):309-313. doi: 10.1016/j.pathol.2016.10.013. Epub 2017 Feb 23.
Clostridium difficile infection (CDI) has risen in prominence in Australia recently. We conducted laboratory-based surveillance of CDI to examine C. difficile circulating in Australia in October/November 2012. We collected 542 isolates from all States and Territories of Australia except the Northern Territory. The most common ribotypes (RTs) were RTs 014/020 (25.5%), 002 (10.5%), 056 (5.9%) and 070 (4.2%). The survey results were compared with results from a similar Australian survey conducted in 2010. Proportions of RTs 014/020 and 002 remained similar, while RTs 056 (5.9%), 015 (4.1%), 017 (3.3%) and 244 (2.4%) increased in prevalence. Basic clinical and demographic data were available for 338 cases. The majority were healthcare facility-associated (HCFA-CDI, 51.5%) while 17.5% were community-associated (CA-CDI). While no RTs were associated with CA-CDI, RTs 056 and 126 were recently found in Australian production animals, indicating a possible community health threat in Australia.
艰难梭菌感染（CDI）近来在澳大利亚愈发突出。我们开展了基于实验室的CDI监测，以研究2012年10月/11月在澳大利亚传播的艰难梭菌。我们从澳大利亚除北领地外的所有州和领地收集了542株分离株。最常见的核糖体分型（RTs）为RTs 014/020（25.5%）、002（10.5%）、056（5.9%）和070（4.2%）。将此次调查结果与2010年澳大利亚开展的一项类似调查结果进行了比较。RTs 014/020和002的比例保持相似，而RTs 056（5.9%）、015（4.1%）、017（3.3%）和244（2.4%）的流行率有所上升。有338例病例的基本临床和人口统计学数据。大多数病例与医疗机构相关（HCFA-CDI，51.5%），而17.5%为社区相关（CA-CDI）。虽然没有RTs与CA-CDI相关，但最近在澳大利亚的生产动物中发现了RTs 056和126，这表明对澳大利亚社区健康可能构成威胁。
