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本文引用的文献

1
Enterohemorrhagic Escherichia coli Hybrid Pathotype O80:H2 as a New Therapeutic Challenge.肠出血性大肠杆菌杂交致病型O80:H2——一种新的治疗挑战
Emerg Infect Dis. 2016 Sep;22(9):1604-12. doi: 10.3201/eid2209.160304.
2
Shiga Toxin 1-Producing Shigella sonnei Infections, California, United States, 2014-2015.2014 - 2015年美国加利福尼亚州产志贺毒素1的宋内志贺菌感染情况
Emerg Infect Dis. 2016 Apr;22(4):679-86. doi: 10.3201/eid2204.151825.
3
Shiga toxins: from structure and mechanism to applications.志贺毒素:从结构、作用机制到应用
Appl Microbiol Biotechnol. 2016 Feb;100(4):1597-1610. doi: 10.1007/s00253-015-7236-3. Epub 2015 Dec 19.
4
Stx-Producing Shigella Species From Patients in Haiti: An Emerging Pathogen With the Potential for Global Spread.来自海地患者的产志贺毒素志贺氏菌属:一种有全球传播潜力的新兴病原体。
Open Forum Infect Dis. 2015 Sep 19;2(4):ofv134. doi: 10.1093/ofid/ofv134. eCollection 2015 Dec.
5
Characterization of Shigella sonnei Isolate Carrying Shiga Toxin 2-Producing Gene.携带志贺毒素2产生基因的宋内志贺菌分离株的特性分析
Emerg Infect Dis. 2015 May;21(5):891-2. doi: 10.3201/eid2105.140621.
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Shiga Toxin (Stx) Classification, Structure, and Function.志贺毒素(Stx)分类、结构与功能。
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Syndromes of thrombotic microangiopathy.血栓性微血管病的综合征。
N Engl J Med. 2014 Aug 14;371(7):654-66. doi: 10.1056/NEJMra1312353.
8
Shiga toxin 2-encoding bacteriophages in human fecal samples from healthy individuals.健康个体粪便样本中的志贺毒素 2 编码噬菌体。
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Gastrointestinal and extra-intestinal manifestations of childhood shigellosis in a region where all four species of Shigella are endemic.在所有四种志贺菌流行的地区,儿童志贺菌病的胃肠道和肠道外表现。
PLoS One. 2013 May 17;8(5):e64097. doi: 10.1371/journal.pone.0064097. Print 2013.
10
Comparison of three different methods for detection of Shiga toxin-producing Escherichia coli in a tertiary pediatric care center.三种不同方法在一家三级儿科护理中心检测产志贺毒素大肠埃希菌的比较。
J Clin Microbiol. 2013 Feb;51(2):481-6. doi: 10.1128/JCM.02219-12. Epub 2012 Nov 21.

以及溶血性尿毒症综合征:一例病例报告及文献综述。

and hemolytic uremic syndrome: A case report and literature review.

作者信息

Adams Casey, Vose Aaron, Edmond Michael B, Lyckholm Laurel

机构信息

Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.

Department of Infectious Diseases, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.

出版信息

IDCases. 2017 Feb 10;8:6-8. doi: 10.1016/j.idcr.2017.02.003. eCollection 2017.

DOI:10.1016/j.idcr.2017.02.003
PMID:28239557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5322170/
Abstract

Hemolytic uremic syndrome (HUS) is a well-described process that is known to cause severe renal dysfunction, thrombocytopenia, and anemia. HUS is typically associated with toxins (shiga-like and shigella toxin) found in strains of and spp [1], [2], [3]. We present a case of a 27 year-old man with jaundice, thrombocytopenia, and renal dysfunction who was found to have HUS in the setting of infection. Outside of developing countries, cases of HUS related to are largely unreported.

摘要

溶血尿毒综合征(HUS)是一个已被充分描述的过程,已知会导致严重的肾功能障碍、血小板减少和贫血。HUS通常与在大肠杆菌和志贺氏菌属菌株中发现的毒素(志贺样毒素和志贺毒素)有关[1,2,3]。我们报告一例27岁男性病例,该患者有黄疸、血小板减少和肾功能障碍,在感染大肠杆菌的情况下被诊断为HUS。在发展中国家以外,与大肠杆菌相关的HUS病例基本未被报道。