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开始接受透析治疗的患者的抑郁、焦虑及与健康相关的生活质量

Depression, anxiety and health-related quality of life amongst patients who are starting dialysis treatment.

作者信息

Rebollo Rubio Ana, Morales Asencio José Miguel, Eugenia Pons Raventos Ma

机构信息

Department of Nephrology, Carlos Haya Regional University Hospital and University of Málaga, Málaga, Spain.

Faculty of Health Sciences, University of Málaga, Málaga, Spain.

出版信息

J Ren Care. 2017 Jun;43(2):73-82. doi: 10.1111/jorc.12195. Epub 2017 Feb 27.

DOI:10.1111/jorc.12195
PMID:28239953
Abstract

BACKGROUND

Chronic kidney disease (CKD) has a severe impact on patients' health-related quality of life (HRQL). The start of renal replacement therapy (RRT) significantly influences psychological, physical and social aspects of life.

OBJECTIVES

To analyse the HRQL and psychological status (anxiety and depression) at the start of RRT.

METHODS

We undertook an observational descriptive cross-sectional study. A total of 152 patients starting RRT were recruited for the study. HRQL was measured by the Kidney Disease and Quality of Life Short Form questionnaire. Levels of anxiety and depression were assessed by the Hospital Anxiety and Depression Scale questionnaire. Comorbidities and sociodemographic and clinical factors were also evaluated.

FINDINGS

HRQL in patients with end-stage kidney disease (ESKD) is significantly affected by the initiation of RRT in all respects. States of anxiety and depression were present in 26.6% and 27% of patients, respectively. These states are significantly related to the emotional component of the quality of life.

CONCLUSION

The initiation of RRT has a strong impact on HRQL in comparison with a reference population and with other stages of CKD. The early detection of an altered psychological state is important, as this condition should be treated from the first stages of the disease, as it can significantly affect the subsequent development of RRT and the patient's quality of life.

摘要

背景

慢性肾脏病(CKD)对患者的健康相关生活质量(HRQL)有严重影响。肾脏替代治疗(RRT)的开始对生活的心理、身体和社会方面有显著影响。

目的

分析RRT开始时的HRQL和心理状态(焦虑和抑郁)。

方法

我们进行了一项观察性描述性横断面研究。共招募了152名开始接受RRT的患者进行研究。HRQL通过肾脏病与生活质量简表问卷进行测量。焦虑和抑郁水平通过医院焦虑抑郁量表问卷进行评估。还评估了合并症以及社会人口学和临床因素。

结果

终末期肾病(ESKD)患者的HRQL在各个方面均受到RRT开始的显著影响。分别有26.6%和27%的患者存在焦虑和抑郁状态。这些状态与生活质量的情感成分显著相关。

结论

与参考人群和CKD的其他阶段相比,RRT的开始对HRQL有强烈影响。早期发现心理状态改变很重要,因为这种情况应在疾病的第一阶段就进行治疗,因为它会显著影响RRT的后续发展和患者的生活质量。

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