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对禽急性白血病病毒转化的细胞具有特异性的表观DNA结合蛋白。

Apparent DNA-binding protein specific for cells transformed by avian acute leukemia viruses.

作者信息

Benedict S H

机构信息

Department of Pediatrics, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado 80206.

出版信息

Cancer Res. 1987 Dec 15;47(24 Pt 1):6586-9.

PMID:2824037
Abstract

An apparent DNA-binding protein is described that is specific for cells transformed by avian acute leukemia viruses. This protein cannot be demonstrated in cells transformed by any of the avian sarcoma viruses or in cells infected with nontransforming avian retroviruses. The protein also is not detectable in noninfected quail or chicken embryo primary cultures or in noninfected chicken hematopoietic cells. The apparent molecular weight of this protein is 105,000 and it is referred to as DBP105.

摘要

描述了一种明显的DNA结合蛋白,它对禽急性白血病病毒转化的细胞具有特异性。在由任何禽肉瘤病毒转化的细胞或感染非转化性禽逆转录病毒的细胞中均未检测到这种蛋白。在未感染的鹌鹑或鸡胚原代培养物或未感染的鸡造血细胞中也检测不到这种蛋白。这种蛋白的表观分子量为105,000,被称为DBP105。

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