Pailee Phanruethai, Mahidol Chulabhorn, Ruchirawat Somsak, Prachyawarakorn Vilailak
Laboratory of Natural Products, Chulabhorn Research Institute, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand.
Chemical Biology Program, Chulabhorn Graduate Institute, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand.
Mar Drugs. 2017 Feb 23;15(3):54. doi: 10.3390/md15030054.
Eight new sterols (- and -), together with eight known compounds (- and -) were isolated from marine sponge sp. The structures of these compounds were elucidated on the basis of extensive spectroscopic analysis. The cytotoxicity of some compounds against a panel of human cancer cell lines is also reported.
从海洋海绵物种中分离出8种新的甾醇(-和-)以及8种已知化合物(-和-)。基于广泛的光谱分析阐明了这些化合物的结构。还报道了一些化合物对一组人类癌细胞系的细胞毒性。