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一项评估孕产妇牙周状况及其妊娠结局并进行相关性分析的前瞻性队列研究。

A Prospective Cohort Study to Assess and Correlate the Maternal Periodontal Status with Their Pregnancy Outcome.

作者信息

Lohana M H, Suragimath G, Patange R P, Varma S, Zope S A

机构信息

Department of Periodontology, School of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, India.

Department of Obstetrics and Gynaecology, Krishna Institute of Medical Sciences Deemed University, Karad, India.

出版信息

J Obstet Gynaecol India. 2017 Feb;67(1):27-32. doi: 10.1007/s13224-016-0920-0. Epub 2016 Jun 30.

Abstract

BACKGROUND

There is an overwhelming body of evidence strongly suggesting that periodontal infection may have a significant negative impact on pregnancy outcome in some women. The aim of this study was to determine the association between periodontal disease and preterm low birth weight of babies.

MATERIALS AND METHODS

A total of 300 pregnant women, between 20 and 24 weeks of gestation i.e., second trimester, were considered for the study. The periodontal status was recorded using the following parameters: probing pocket depth, clinical attachment level, oral hygiene index and plaque index. After initial examination in the second trimester, the pregnant women were followed till delivery of the baby. Postpartum data i.e., weight of baby, gestational age of pregnancy and type of delivery, were recorded.

RESULTS

Out of 300 pregnant women, 248 women had full-term delivery (12 low birth weight and 236 normal birth weight) while 52 had preterm delivery (6 normal birth weight and 46 low birth weight). There was significant association between body mass index and level of periodontal disease severity of pregnant women with birth weight of babies, gestational age of pregnant women and mode of delivery, respectively. As the level of periodontal disease severity increased, the proportion of delivering preterm and low birth weight babies also increased.

CONCLUSION

The conclusions obtained revealed that Periodontal disease is a potential risk factor for preterm low birth weight babies of pregnant women.

摘要

背景

大量证据有力地表明,牙周感染可能对部分女性的妊娠结局产生重大负面影响。本研究的目的是确定牙周疾病与婴儿早产低体重之间的关联。

材料与方法

本研究共纳入300名妊娠20至24周(即孕中期)的孕妇。使用以下参数记录牙周状况:探诊深度、临床附着水平、口腔卫生指数和菌斑指数。在孕中期进行初次检查后,对孕妇进行随访直至婴儿出生。记录产后数据,即婴儿体重、妊娠孕周和分娩方式。

结果

300名孕妇中,248名妇女足月分娩(12名低体重儿和236名正常体重儿),而52名早产(6名正常体重儿和46名低体重儿)。孕妇的体重指数与牙周疾病严重程度水平分别与婴儿出生体重、孕妇妊娠孕周和分娩方式之间存在显著关联。随着牙周疾病严重程度水平的增加,早产和低体重儿的比例也增加。

结论

所得结论表明,牙周疾病是孕妇早产低体重儿的一个潜在风险因素。

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