Lenzi R, Marchetti M, Muscatello L
Division of Otorhinolaryngology,Azienda USL Toscana Nord Ovest,Ospedale delle Apuane,Massa,Italy.
J Laryngol Otol. 2017 Apr;131(4):368-371. doi: 10.1017/S002221511700024X.
Occult differentiated thyroid carcinomas are not uncommon. The initial presentation of a thyroid carcinoma is often detection of a metastatic cervical lymph node.
A retrospective review was performed of the medical records of 304 patients who underwent neck dissection between 1996 and 2008 for squamous cell carcinoma of the head and neck.
Ten patients (3.3 per cent) had nodal metastasis originating from papillary thyroid cancer. All of these patients underwent thyroidectomy and post-operative 131iodine radiometabolic therapy. No patient developed a thyroid tumour after surgery.
Despite its metastatic spread, thyroid cancer does not affect the overall prognosis of patients who are already being treated for a more aggressive malignancy. However, in otherwise healthy patients, it is worth treating this second malignancy to avoid potential complications related to local disease or metastatic thyroid cancer.
隐匿性分化型甲状腺癌并不罕见。甲状腺癌的最初表现通常是发现颈部转移性淋巴结。
对1996年至2008年间因头颈部鳞状细胞癌接受颈部清扫术的304例患者的病历进行回顾性研究。
10例患者（3.3%）出现源自甲状腺乳头状癌的淋巴结转移。所有这些患者均接受了甲状腺切除术及术后131碘放射性代谢治疗。术后无患者发生甲状腺肿瘤。
尽管甲状腺癌已发生转移播散，但对于已在接受更具侵袭性恶性肿瘤治疗的患者，其并不影响总体预后。然而，对于其他方面健康的患者，治疗这种第二种恶性肿瘤是值得的，以避免与局部疾病或转移性甲状腺癌相关的潜在并发症。
