Pastula Daniel M, Hancock W Thane, Bel Martin, Biggs Holly, Marfel Maria, Lanciotti Robert, Laven Janeen, Chen Tai-Ho, Staples J Erin, Fischer Marc, Hills Susan L
Epidemic Intelligence Service Program Office, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, United States of America.
Arboviral Diseases Branch, Division of Vector-Borne Diseases (DVBD), CDC, Fort Collins, Colorado, United States of America.
PLoS Negl Trop Dis. 2017 Mar 1;11(3):e0005410. doi: 10.1371/journal.pntd.0005410. eCollection 2017 Mar.
Chikungunya virus is a mosquito-borne alphavirus which causes an acute febrile illness associated with polyarthralgia. Beginning in August 2013, clinicians from the Yap State Department of Health in the Federated States of Micronesia (FSM) identified an unusual cluster of illness which was subsequently confirmed to be chikungunya virus disease. Chikungunya virus disease previously had not been recognized in FSM.
METHODOLOGY/PRINCIPAL FINDINGS: Information from patients presenting to healthcare facilities was collected and analyzed. During August 11, 2013, to August 10, 2014, a total of 1,761 clinical cases were reported for an attack rate of 155 clinical cases per 1,000 population. Among residents of Yap Main Island, 3% were hospitalized. There were no deaths. The outbreak began on Yap Main Island and rapidly spread throughout Yap Main Island and to three neighboring islands.
CONCLUSIONS/SIGNIFICANCE: Chikungunya virus can cause explosive outbreaks with substantial morbidity. Given the increasing globalization of chikungunya virus, strong surveillance systems and access to laboratory testing are essential to detect outbreaks.
基孔肯雅病毒是一种通过蚊子传播的甲病毒，可引发与多关节痛相关的急性发热疾病。2013年8月起，密克罗尼西亚联邦雅浦州卫生部的临床医生发现了一组不寻常的病例群，随后确诊为基孔肯雅病毒病。此前，基孔肯雅病毒病在密克罗尼西亚联邦尚未被发现。
方法/主要发现：收集并分析了前往医疗机构就诊患者的信息。在2013年8月11日至2014年8月10日期间，共报告了1761例临床病例，发病率为每1000人中有155例临床病例。在雅浦主岛居民中，3%的人住院治疗。无死亡病例。疫情始于雅浦主岛，并迅速蔓延至整个雅浦主岛及三个相邻岛屿。
结论/意义：基孔肯雅病毒可引发具有高发病率的爆发性疫情。鉴于基孔肯雅病毒全球化趋势日益增强，强大的监测系统和实验室检测手段对于发现疫情至关重要。
