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旅行者感染基孔肯雅热-美国,2014-2016 年。

Chikungunya Virus Disease among Travelers-United States, 2014-2016.

机构信息

Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado.

出版信息

Am J Trop Med Hyg. 2018 Jan;98(1):192-197. doi: 10.4269/ajtmh.17-0668. Epub 2018 Jan 1.

Abstract

Chikungunya virus is a mosquito-borne alphavirus that causes an acute febrile illness with severe polyarthralgia. The first local transmission of chikungunya virus in the Western Hemisphere was reported in December 2013. In the following year, the virus spread throughout much of the Americas and the number of cases among travelers increased substantially. We reviewed the epidemiology of chikungunya virus disease cases reported among U.S. travelers from 2014 to 2016. A total of 3,941 travel-acquired cases were reported from 49 states and the District of Columbia; 3,616 (92%) reported travel to other countries or territories in the Americas; the remaining 8% reported travel to Asia, Africa, or the Western Pacific. The most commonly reported travel destinations were the Dominican Republic, Puerto Rico, and Haiti. The largest number of cases ( = 2,780, 71%) had illness onset in 2014, followed by 2015 ( = 913, 23%) and 2016 ( = 248, 6%). Cases occurred in every month, but 70% of case-patients had illness onset from April to September, the months when mosquitoes are most likely to be active in the continental United States. Travel-acquired chikungunya cases will likely continue to occur and present a risk of introduction of the virus to locations in the continental United States. Clinicians and public health officials should be educated about the recognition, diagnosis, management, and timely reporting of chikungunya cases.

摘要

基孔肯雅热病毒是一种经蚊传播的甲病毒,可引起伴有严重多发性关节炎的急性发热性疾病。西半球首例基孔肯雅热病毒本地传播于 2013 年 12 月报告。次年,该病毒在美洲大部分地区传播,旅行者中的病例数大幅增加。我们对 2014 年至 2016 年期间美国旅行者报告的基孔肯雅热病毒病病例的流行病学进行了回顾。从 49 个州和哥伦比亚特区共报告了 3941 例旅行获得的病例;3616 例(92%)报告旅行到美洲其他国家或地区;其余 8%报告旅行到亚洲、非洲或西太平洋。报告的最常见旅行目的地是多米尼加共和国、波多黎各和海地。最多的病例(2780 例,71%)发病于 2014 年,其次是 2015 年(913 例,23%)和 2016 年(248 例,6%)。病例发生在每个月,但 70%的病例发病于 4 月至 9 月,这是美国大陆蚊子最活跃的月份。可能会继续发生旅行获得的基孔肯雅热病例,并对美国大陆的某些地区带来病毒传入的风险。临床医生和公共卫生官员应接受有关基孔肯雅热病例的识别、诊断、管理和及时报告的教育。

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