基因组测序技术与护理：护士及护士科学家的角色是什么？
Genome Sequencing Technologies and Nursing: What Are the Roles of Nurses and Nurse Scientists?
作者信息
Taylor Jacquelyn Y, Wright Michelle L, Hickey Kathleen T, Housman David E
机构信息
Jacquelyn Y. Taylor, PhD, PNP-BC, RN, FAHA, FAAN, is Associate Professor and Associate Dean of Diversity and Inclusion, School of Nursing, Yale University, Orange, Connecticut. Michelle L. Wright, PhD, RN, is Assistant Research Professor, School of Nursing, Emory University, Atlanta, Georgia. She was a Postdoctoral Associate, School of Nursing, Yale University, Orange, Connecticut, at the time this work was completed Kathleen T. Hickey, EdD, FNP, ANP, FAHA, FAAN, is Associate Professor, School of Nursing, Columbia University, New York, New York. David E. Housman, PhD, is Virginia and D. K. Ludwig Scholar for Cancer Research and Professor of Biology, Department of Biology, Massachusetts Institute of Technology, Cambridge.
出版信息
Nurs Res. 2017 Mar/Apr;66(2):198-205. doi: 10.1097/NNR.0000000000000211.
BACKGROUND
Advances in DNA sequencing technology have resulted in an abundance of personalized data with challenging clinical utility and meaning for clinicians. This wealth of data has potential to dramatically impact the quality of healthcare. Nurses are at the focal point in educating patients regarding relevant healthcare needs; therefore, an understanding of sequencing technology and utilizing these data are critical.
AIM
The objective of this study was to explicate the role of nurses and nurse scientists as integral members of healthcare teams in improving understanding of DNA sequencing data and translational genomics for patients.
APPROACH
A history of the nurse role in newborn screening is used as an exemplar.
DISCUSSION
This study serves as an exemplar on how genome sequencing has been utilized in nursing science and incorporates linkages of other omics approaches used by nurses that are included in this special issue. This special issue showcased nurse scientists conducting multi-omic research from various methods, including targeted candidate genes, pharmacogenomics, proteomics, epigenomics, and the microbiome. From this vantage point, we provide an overview of the roles of nurse scientists in genome sequencing research and provide recommendations for the best utilization of nurses and nurse scientists related to genome sequencing.
背景
DNA测序技术的进步产生了大量个性化数据，但其临床实用性和对临床医生的意义颇具挑战性。这些丰富的数据有可能极大地影响医疗保健质量。护士在教育患者了解相关医疗保健需求方面处于核心地位；因此，理解测序技术并利用这些数据至关重要。
目的
本研究的目的是阐明护士和护士科学家作为医疗团队不可或缺的成员，在提高患者对DNA测序数据和转化基因组学的理解方面所发挥的作用。
方法
以护士在新生儿筛查中的角色历史为例。
讨论
本研究是关于基因组测序如何在护理科学中得到应用的一个范例，并纳入了本期特刊中护士所使用的其他组学方法的联系。本期特刊展示了护士科学家通过各种方法进行多组学研究，包括靶向候选基因、药物基因组学、蛋白质组学、表观基因组学和微生物组学。从这个角度出发，我们概述了护士科学家在基因组测序研究中的作用，并为护士和护士科学家在基因组测序方面的最佳利用提供建议。
Zotero 插件