Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
J Magn Reson Imaging. 2017 Nov;46(5):1441-1447. doi: 10.1002/jmri.25689. Epub 2017 Mar 6.
To compare bicomponent ultrashort echo time (UTE) T2* parameters of patellar tendon between healthy volunteers and patients with patellar tendinopathy.
This study was performed with Institutional Review Board approval and with all subjects signing informed consent. A UTE- T2* mapping sequence was performed at 3.0T on the knees of 10 healthy volunteers and in 11 patients with patellar tendinopathy. The UTE- T2* relaxation times of the fast relaxing macromolecular bound water component ( T2F) and the slow relaxing bulk water component ( T2S) and the fraction of the fast relaxing macromolecular bound water component (F ) of patellar tendon were measured in all subjects. Wilcoxon rank-sum tests were used to compare UTE- T2* parameters between healthy volunteers and patients with patellar tendinopathy.
Mean T2F, T2S, and F of the patellar tendon was 1.5 msec, 23.1 msec, and 79.5%, respectively, for healthy volunteers and 1.9 msec, 22.3 msec, and 75.5%, respectively, for patients with patellar tendinopathy. There were statistically significant differences between groups of subjects for T2F (P = 0.01) and F (P = 0.007) but not T2S (P = 0.10) of the patellar tendon.
Patients with patellar tendinopathy had significantly higher T2F and significantly lower F of patellar tendon than healthy volunteers, which suggests that bicomponent UTE- T2 parameters can detect changes in the composition and microstructure of degenerative tendon.
1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2017;46:1441-1447.
比较健康志愿者与髌腱病患者髌腱的双组份超短回波时间（UTE）T2*参数。
本研究经机构审查委员会批准，所有受试者均签署知情同意书。在 3.0T 磁共振扫描仪上对 10 名健康志愿者和 11 名髌腱病患者的膝关节进行 UTE-T2* 图谱序列扫描。在所有受试者中测量髌腱快弛豫大分子结合水成分（T2F）、慢弛豫体相水成分（T2S）和快弛豫大分子结合水成分分数（F）的 UTE-T2弛豫时间。采用 Wilcoxon 秩和检验比较健康志愿者与髌腱病患者的 UTE-T2参数。
健康志愿者的髌腱 T2F、T2S 和 F 的平均值分别为 1.5 msec、23.1 msec 和 79.5%，髌腱病患者分别为 1.9 msec、22.3 msec 和 75.5%。两组受试者的 T2F（P=0.01）和 F（P=0.007）差异有统计学意义，而 T2S（P=0.10）差异无统计学意义。
与健康志愿者相比，髌腱病患者髌腱的 T2F 明显升高，F 明显降低，这提示双组份 UTE-T2参数可检测退变肌腱的成分和微观结构变化。
1 技术功效：2 级 J. 磁共振成像 2017；46：1441-1447。
