Giovannini Niccolò, Schwartz Lianne, Cipriani Sonia, Parazzini Fabio, Baini Ilaria, Signorelli Valentina, Cetin Irene
a Dipartimento Materno infantile IRCCS Fondazione Policlinico Mangiagalli Regina Elena , Università degli Studi di Milano , Milano , Italy.
b School of Nursing and Midwifery, Griffith University , Brisbane , Australia.
J Matern Fetal Neonatal Med. 2018 Mar;31(5):651-655. doi: 10.1080/14767058.2017.1293032. Epub 2017 Apr 10.
This prospective study aims to analyze the relation between particulate matter (PM) exposure during pregnancy and birth weight (BW), placental weight (PW) and umbilical artery PH (UAPH).
Population included 3614 women born in Italy, living in Lombardia Region, consecutively admitted to the Clinica Mangiagalli for an elective cesarean section from January 2004 through December 2006. Outdoor air quality data were provided by the Department of the Regional Environmental Protection Agency and obtained by a network of fixed monitoring stations representatively distributed in eight geographical areas.
Birth weight was negatively associated with exposure to PM concentration during the first trimester of pregnancy (mean change -22.2 g, 95%CI -8.7 to -35.7, p = 0.0013). Placental weight and umbilical artery PH were not associated with exposure to PM concentration. Fetal weight was negatively associated with exposure to PM concentration during the first trimester of pregnancy.
