Zheng Yurong, Mo Wenju, Yu Yang, Zou Dehong, He Xiangming, Xia Xianghou, Hu Jiejie
a Department of Breast Surgery , Zhejiang Cancer Hospital , Hangzhou , China.
Cancer Biol Ther. 2017 Mar 4;18(3):132-136. doi: 10.1080/15384047.2017.1294284. Epub 2017 Feb 17.
We report a 28-year-old woman who presented with a 6-year history of milk-like discharge from both of her nipples and was diagnosed with prolactinoma based on computed tomography (CT) findings and serum prolactin level. Further breast examination revealed a mass located in the upper outer region of the left breast. She underwent subtotal pituitary tumor resection. Thereafter, modified radical mastectomy was performed for left breast cancer. Twelve years after treatment, prolactinoma recurrence was detected, and bromocriptine therapy was administered. No recurrence of breast cancer was discovered. Based on this case report, we stress the importance of prolactin levels due to their possible biologic effects on breast cancer induction or growth.
我们报告一名28岁女性,她有6年双侧乳头出现乳样溢液的病史,根据计算机断层扫描(CT)结果和血清催乳素水平被诊断为催乳素瘤。进一步的乳房检查发现左乳房外上区域有一个肿块。她接受了垂体肿瘤次全切除术。此后,对左乳腺癌进行了改良根治性乳房切除术。治疗12年后,检测到催乳素瘤复发,并给予溴隐亭治疗。未发现乳腺癌复发。基于本病例报告,我们强调催乳素水平的重要性,因为它们可能对乳腺癌的诱发或生长产生生物学影响。