Pahlevan Sharif Saeed
Taylor's Business School, Taylor's University Lakeside Campus, No. 1 Jalan Taylors, 47500 Subang Jaya, Selangor, Malaysia.
Eur J Oncol Nurs. 2017 Apr;27:28-35. doi: 10.1016/j.ejon.2017.01.005. Epub 2017 Feb 9.
The main objective of this study was to investigate the mediating role of uncertainty in the relationship between locus of control with quality of life, anxiety, and depression.
A descriptive and correlational survey was conducted in a private hospital in Kuala Lumpur, Malaysia. A convenience sample of 118 Malaysian breast cancer patients voluntarily participated in the study and responded to a set of questionnaires including: socio-demographic questionnaire, the short form of Locus of Control Scale, the Functional Assessment of Cancer Therapy-Breast (FACT-B), the Hospital Anxiety and Depression Scale (HADS), and the Short-Form Mishel Uncertainty in Illness Scale (SF-MUIS).
The results revealed that breast cancer patients with higher internal locus of control and lower external locus of control experience a higher quality of life, lower anxiety, and lower depression. Also, uncertainty mediated the relationship between locus of control with quality of life and depression (quasi-significant).
The findings indicated the need for early, targeted psychological interventions seeking to gradually shift cancer patients' locus of control from external to internal in order to improve their quality of life and reduce their depression and anxiety. Moreover, health care providers by providing relevant information to cancer patients, especially for externally oriented patients, can reduce their uncertainty which in turn would improve their quality of life.
本研究的主要目的是探讨不确定性在控制点与生活质量、焦虑和抑郁之间关系中的中介作用。
在马来西亚吉隆坡的一家私立医院进行了一项描述性和相关性调查。118名马来西亚乳腺癌患者的便利样本自愿参与了该研究，并回答了一系列问卷，包括：社会人口学问卷、控制点量表简表、癌症治疗功能评估-乳腺（FACT-B）、医院焦虑抑郁量表（HADS）以及疾病不确定感简易量表（SF-MUIS）。
结果显示，具有较高内控点和较低外控点的乳腺癌患者生活质量更高，焦虑和抑郁程度更低。此外，不确定性在控制点与生活质量和抑郁之间的关系中起中介作用（接近显著）。
研究结果表明，需要进行早期、有针对性的心理干预，旨在逐步将癌症患者的控制点从外部转向内部，以提高他们的生活质量，减轻他们的抑郁和焦虑。此外，医疗保健提供者通过向癌症患者，特别是外向型患者提供相关信息，可以降低他们的不确定性，进而改善他们的生活质量。
