食管癌和胃癌的筛查与预防策略
Screening and Preventive Strategies in Esophagogastric Cancer.
作者信息
Zakko Liam, Lutzke Lori, Wang Kenneth K
机构信息
Division of Gastroenterology and Hepatology, Mayo Clinic, 200 2nd St. SW, Rochester, MN 55905, USA.
Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street Northwest, Rochester, MN, USA.
出版信息
Surg Oncol Clin N Am. 2017 Apr;26(2):163-178. doi: 10.1016/j.soc.2016.10.004.
Abstract
Gastric adenocarcinoma, esophageal adenocarcinoma, and esophageal squamous cell carcinoma are among the most prevalent and deadly of malignancies worldwide. Screening and prevention programs will be critical to finally improving outcomes in these diseases. For gastric adenocarcinoma, screening in high-risk populations has significantly reduced mortality. More research is needed on screening high-risk individuals in low-risk populations. For esophageal adenocarcinoma, work is needed to develop efficient and effective techniques in mass screening programs. For most Western populations, current screening is not cost effective. Avoiding environmental risk factors is critical to reducing the incidence of this deadly illness.
摘要
胃腺癌、食管腺癌和食管鳞状细胞癌是全球最常见且致命的恶性肿瘤之一。筛查和预防计划对于最终改善这些疾病的治疗效果至关重要。对于胃腺癌，在高危人群中进行筛查已显著降低了死亡率。在低风险人群中筛查高危个体还需要更多研究。对于食管腺癌，需要开展工作以在大规模筛查计划中开发高效有效的技术。对于大多数西方人群而言，目前的筛查并不具有成本效益。避免环境风险因素对于降低这种致命疾病的发病率至关重要。
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Gastroenterology. 2017 Jan;152(1):24-26. doi: 10.1053/j.gastro.2016.11.001. Epub 2016 Nov 5.
2
Screening and surveillance for gastric cancer in the United States: Is it needed?美国胃癌的筛查与监测：有必要吗？
Gastrointest Endosc. 2016 Jul;84(1):18-28. doi: 10.1016/j.gie.2016.02.028. Epub 2016 Mar 3.
3
Population-wide Impact of Long-term Use of Aspirin and the Risk for Cancer.阿司匹林长期使用对人群的影响及癌症风险。
JAMA Oncol. 2016 Jun 1;2(6):762-9. doi: 10.1001/jamaoncol.2015.6396.
4
Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance.幽门螺杆菌相关的胃黏膜肠化生：治疗与监测
World J Gastroenterol. 2016 Jan 21;22(3):1311-20. doi: 10.3748/wjg.v22.i3.1311.
5
Environmental risk factors for oesophageal cancer in Malawi: A case-control study.马拉维食管癌的环境风险因素：一项病例对照研究。
Malawi Med J. 2015 Sep;27(3):88-92. doi: 10.4314/mmj.v27i3.3.
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