Rapone B, Nardi G M, DI Venere D, Pettini F, Grassi F R, Corsalini M
Interdisciplinary Department of Medicine (DIM) - Section of Dentistry, University "Aldo Moro" of Bari, Bari, Italy.
Department of Dental and Maxillofacial Sciences, "Sapienza" University of Rome, Rome, Italy.
Oral Implantol (Rome). 2017 Feb 14;9(Suppl 1/2016 to N 4/2016):90-97. doi: 10.11138/orl/2016.9.1S.090. eCollection 2016 Jan-Mar.
This study was aimed at assessing the effectiveness and the importance of an oral hygiene (OH) protocol in patients undergoing radiation therapy and chemotherapy after prosthesis rehabilitation, in order to reduce or minimize oral complications.
This study was carried out at the Department of Dental Science, at the University of Bari-Italy from December 2012 to December 2015 on 34 selected patients with primary oral cancer undergoing chemotherapy and radiotherapy after prosthesis rehabilitation. They were divided into 2 groups according to their age, sex and cancer therapy. Seventeen patients were assigned to the control group and seventeen in the experimental one. In the experimental group (Table 1), patients underwent an oral hygiene protocol whereas in the control group (Table 2) patients received the usual care provided within the clinical setting. All the patients gave written informed consent. It has been asked and obtained the authorisation from the Ethics Committee of the Dental Science and Surgery Department.
Results show that in patients undergoing the oral hygiene protocol, the complications and the risks of infection and permanent dental problems have been minimized. Indeed, of the seventeen patients undergoing the OH protocol, 70% obtained positive results and were satisfied with the program outcome.
The role of the health care providers is essential to educate patients to adhere to the prescribed treatments and reinforce their motivation in oral hygiene. The oral hygiene procedures prevent and ameliorate oral complications due to the radiation therapy and chemotherapy.
本研究旨在评估口腔卫生（OH）方案在假体修复后接受放疗和化疗的患者中的有效性和重要性，以减少或最小化口腔并发症。
本研究于2012年12月至2015年12月在意大利巴里大学牙科学系对34例选定的原发性口腔癌患者进行，这些患者在假体修复后接受化疗和放疗。根据年龄、性别和癌症治疗情况将他们分为2组。17例患者被分配到对照组，17例在实验组。在实验组（表1）中，患者接受口腔卫生方案，而在对照组（表2）中，患者接受临床环境中提供的常规护理。所有患者均签署了书面知情同意书。已向牙科学与外科学系伦理委员会提出申请并获得批准。
结果表明，在接受口腔卫生方案的患者中，并发症以及感染和永久性牙齿问题的风险已降至最低。事实上，在接受OH方案的17例患者中，70%取得了阳性结果，并对方案结果感到满意。
医护人员的作用对于教育患者坚持规定的治疗并增强他们在口腔卫生方面的积极性至关重要。口腔卫生程序可预防和改善放疗和化疗引起的口腔并发症。
