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绝经后久坐不动的女性在有组织的体育活动期间心血管风险的降低

Cardiovascular risk reduction in sedentary postmenopausal women during organised physical activity.

作者信息

Mazurek Krzysztof, Żmijewski Piotr, Kozdroń Ewa, Fojt Anna, Czajkowska Anna, Szczypiorski Piotr, Mazurek Tomasz

出版信息

Kardiol Pol. 2017;75(5):476-485. doi: 10.5603/KP.a2017.0035. Epub 2017 Mar 10.

Abstract

BACKGROUND

Cardiovascular (CV) diseases are a major cause of death in elderly women. Aerobic training improves component CV risk factors. Long-term, higher-intensity, group-based and home-based exercise training has been shown to improve exer-cise performance. However, it is not clear if short-term, group-based or home-based training with an educational programme permanently improves cardiometabolic parameters in elderly women.

AIM

The aim of the study was to evaluate the effectiveness of organised physical activity programmes dedicated to elderly, sedentary women.

METHODS

Thirty-five sedentary women, aged > 55 years (mean 65.4 ± 7.3 years) were enrolled in a two-week group-based physical training programme of moderate intensity (2.5-5.0 METs) followed by three months of organised, home-based physical activity targeting all major muscle groups with special emphasis on postural muscles, combined with an educational programme about physical activity and CV risk. Eighteen months of self-guided physical activity was the final stage of training. Medical examination and blood samples were collected at baseline and after each step of exercises.

RESULTS

Each step of training resulted in a reduction of systolic and diastolic blood pressure (p < 0.05), body mass index (p < 0.05), waist to hip ratio (p < 0.02), and low-density lipoprotein (p < 0.05) as compared to baseline. The time of exercise (p < 0.01), maximal tolerated load, and maximal oxygen consumption (p < 0.001) were significantly improved after two-weeks of training, as well as the high-density lipoprotein (p < 0.001). These changes remained significant after three months. Finally, the 10-year risk of fatal CV disease reduced significantly (p < 0.05). After 18 months 2/3 of subjects continued physical activity at a sufficient level to achieve additional health benefits according to the World Health Organisation.

CONCLUSIONS

Organised, group-based exercise followed by home-based training and self-guided physical activities constantly improves cardiometabolic parameters and reduces CV risk.

摘要

背景

心血管疾病是老年女性死亡的主要原因。有氧运动训练可改善心血管疾病的危险因素。长期、高强度、基于群体和居家的运动训练已被证明能提高运动表现。然而,尚不清楚短期、基于群体或居家的训练以及教育计划能否持久改善老年女性的心脏代谢参数。

目的

本研究旨在评估针对久坐不动的老年女性的有组织体育活动计划的效果。

方法

35名年龄大于55岁(平均65.4±7.3岁)的久坐不动女性参加了为期两周的中等强度(2.5-5.0代谢当量)的群体体育训练计划,随后进行为期三个月的有组织的居家体育活动,针对所有主要肌肉群,特别强调姿势肌肉,并结合有关体育活动和心血管疾病风险的教育计划。为期18个月的自主体育活动是训练的最后阶段。在基线时以及每一步运动后收集医学检查和血样。

结果

与基线相比,每一步训练均导致收缩压和舒张压降低(p<0.05)、体重指数降低(p<0.05)、腰臀比降低(p<0.02)以及低密度脂蛋白降低(p<0.05)。训练两周后,运动时间(p<0.01)、最大耐受负荷和最大耗氧量(p<0.001)以及高密度脂蛋白(p<0.001)均显著改善。三个月后这些变化仍然显著。最后,致命性心血管疾病的10年风险显著降低(p<0.05)。18个月后,根据世界卫生组织的标准,三分之二的受试者继续进行足够水平的体育活动以获得额外的健康益处。

结论

有组织的群体运动,随后是居家训练和自主体育活动,持续改善心脏代谢参数并降低心血管疾病风险。

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