Stegmann George F, Williams Catherine J A, Franklin Craig, Wang Tobias, Axelsson Michael
Department of Companion Animal Clinical Studies, University of Pretoria.
J S Afr Vet Assoc. 2017 Feb 24;88(0):e1-e6. doi: 10.4102/jsava.v88i0.1451.
A suitable long-term anaesthetic technique was required for implantation of physiological sensors and telemetric devices in sub-adult Nile crocodiles (Crocodylus niloticus) to allow the collection of physiological data. Five Nile crocodiles with a median body mass of 24 kg were used. After manual capture, they were blindfolded and 0.2 mL (1 mg/mL) medetomidine was administered intramuscularly in four of the animals which had an estimated body mass between 20 kg and 30 kg. One crocodile with an estimated body mass of 50 kg received 0.5 mL. For induction, 5 mL propofol (10 mg/mL) was injected intravenously into the occipital sinus. Additional doses were given when required to ensure adequate anaesthesia. Anaesthesia was maintained with 1.5% isoflurane. Ventilation was controlled. Local anaesthesia was administered for surgical incision and external placement of the radio transmitter. Medetomidine was antagonised with atipamezole at the end of surgery. Median heart rate during surgery was 22 beats/min, at extubation 32 beats per min and 30 beats per min the following day at the same body temperature as under anaesthesia. Median body temperature of the animals increased from 27.3 °C to 27.9 °C during anaesthesia, as room temperature increased from 24.5 °C to 29.0 °C during surgery. Anaesthesia was successfully induced with intramuscular medetomidine and intravenous propofol and was maintained with isoflurane for the placement of telemetric implants. Intraoperative analgesia was supplemented with lidocaine infiltration. Perioperative physiological parameters remained stable and within acceptable clinical limits. Multiple factors appear to influence these variables during the recovery period, including residual anaesthetic effects, environmental temperature and physical activity.
为了在亚成年尼罗鳄（尼罗鳄）体内植入生理传感器和遥测设备以收集生理数据，需要一种合适的长期麻醉技术。使用了五只体重中位数为24千克的尼罗鳄。人工捕获后，将它们蒙上眼睛，对四只估计体重在20千克至30千克之间的动物肌肉注射0.2毫升（1毫克/毫升）美托咪定。一只估计体重为50千克的鳄鱼接受了0.5毫升。诱导麻醉时，将5毫升丙泊酚（10毫克/毫升）静脉注射到枕窦。必要时给予额外剂量以确保充分麻醉。用1.5%异氟醚维持麻醉。控制通气。对手术切口和无线电发射器的外部放置进行局部麻醉。手术结束时用阿替美唑拮抗美托咪定。手术期间的心率中位数为每分钟22次，拔管时为每分钟32次，第二天在与麻醉时相同体温下为每分钟30次。麻醉期间动物的体温中位数从27.3℃升至27.9℃，因为手术期间室温从24.5℃升至29.0℃。通过肌肉注射美托咪定和静脉注射丙泊酚成功诱导麻醉，并用异氟醚维持麻醉以放置遥测植入物。术中镇痛辅以利多卡因浸润。围手术期生理参数保持稳定且在可接受的临床范围内。在恢复期，多种因素似乎会影响这些变量，包括残余麻醉效果、环境温度和身体活动。
