衰老对干眼的影响。
Effects of Aging in Dry Eye.
作者信息
de Paiva Cintia S
出版信息
Int Ophthalmol Clin. 2017 Spring;57(2):47-64. doi: 10.1097/IIO.0000000000000170.
Abstract
Dry eye affects millions of people worldwide and causes eye well recognized risk factors for dry eye. Anatomical and inflammation-induced age-related changes affect all components of the lacrimal gland functional unit, inclusive of lacrimal gland, conjunctiva, meibomian gland and compromise ocular surface health. There is increased evidence that inflammation plays a role in dry eye. This review will summarize the current knowledge about aging and dry eye, inclusive of lessons learned from animal models and promising therapies.
摘要
干眼症影响着全球数百万人，并导致人们充分认识到的干眼症风险因素。解剖学和炎症引起的与年龄相关的变化会影响泪腺功能单元的所有组成部分，包括泪腺、结膜、睑板腺，并损害眼表健康。越来越多的证据表明炎症在干眼症中起作用。本综述将总结目前关于衰老和干眼症的知识，包括从动物模型中汲取的经验教训和有前景的治疗方法。
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