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虾青素和维生素E治疗饮食诱导的非酒精性脂肪性肝炎小鼠的肝脏转录组谱

Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E.

作者信息

Kobori Masuko, Takahashi Yumiko, Sakurai Mutsumi, Ni Yinhua, Chen Guanliang, Nagashimada Mayumi, Kaneko Shuichi, Ota Tsuguhito

机构信息

Food Research Institute, National Agriculture and Food Resrach Organization, Tsukuba, Ibaraki 305-8642, Japan.

Department of Cell Metabolism and Nutrition, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan.

出版信息

Int J Mol Sci. 2017 Mar 8;18(3):593. doi: 10.3390/ijms18030593.

Abstract

Astaxanthin alleviates hepatic lipid accumulation and peroxidation, inflammation, and fibrosis in mice with high-cholesterol, high-cholate, and high-fat (CL) diet-induced nonalcoholic steatohepatitis (NASH) [...].

摘要

虾青素可减轻高胆固醇、高胆酸盐和高脂肪(CL)饮食诱导的非酒精性脂肪性肝炎(NASH)小鼠的肝脏脂质积累、过氧化、炎症和纤维化[……]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ed0/5372609/6a28a1eee1fa/ijms-18-00593-g001.jpg

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