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中国南京地区通过膳食暴露对滴滴涕和六六六进行的人体健康风险评估。

Human health risk assessment of DDTs and HCHs through dietary exposure in Nanjing, China.

作者信息

Zhang Qianqian, Xia Zhonghuan, Wu Minmin, Wang Liping, Yang Hao

机构信息

Jiangsu Provincial Key Laboratory of Materials Cycling and Pollution Control, School of Environment, Nanjing Normal University, Nanjing, 210023, China; Key Laboratory of Virtual Geographic Environment (Nanjing Normal University), Ministry of Education, Nanjing, 210023, China.

Jiangsu Provincial Key Laboratory of Materials Cycling and Pollution Control, School of Environment, Nanjing Normal University, Nanjing, 210023, China; Key Laboratory of Virtual Geographic Environment (Nanjing Normal University), Ministry of Education, Nanjing, 210023, China; Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application, Nanjing, 210023, China; State Key Laboratory Cultivation Base of Geographical Environment Evolution (Jiangsu Province), Nanjing, 210023, China.

出版信息

Chemosphere. 2017 Jun;177:211-216. doi: 10.1016/j.chemosphere.2017.03.003. Epub 2017 Mar 6.

DOI:10.1016/j.chemosphere.2017.03.003
PMID:28288429
Abstract

In a market based study in Nanjing, a typical southeast city in China, the most common consumed 23 kinds of foods from eleven different categories (vegetable, fruit, fish, pork, livestock meat, chicken, egg, milk, oil, rice and flour) were sampled in November 2015. The concentrations of DDTs and HCHs in foods were analyzed using gas chromatography with mass spectrometer detector. The residual amounts of DDTs and HCHs in foods were 0.95-3.53 ng g and 0.32-1.96 ng g, respectively. The highest residual of ∑OCPs was 4.75 ng g in livestock meat and the lowest was 1.31 ng g in flour. Estimated daily intakes of both DDTs and HCHs for children were higher than other age groups regardless of the gender. With respect to food categories, the consumption of vegetables generated higher dietary exposure of DDTs and HCHs than other food categories for all age categories, which accounted for 20.21%-29.18% of the total. The daily intakes of γ-HCH and DDTs for all population groups were far below the acceptable amounts suggested by the Food and Agriculture Organization of the United Nations/World Health Organization. Health risk assessment indicated that there was no obvious non-cancer risk for local residents, whereas the cancer risk was estimated to be from 10∼10, being higher than the acceptable risk level and lower than the priority risk level. Among residents of different gender and age, females showed higher risk than males in all age groups, and children were the most vulnerable age group to health risk.

摘要

在一项针对中国东南部典型城市南京的市场调研中,于2015年11月从11个不同类别(蔬菜、水果、鱼类、猪肉、畜肉、鸡肉、蛋类、奶类、食用油、大米和面粉)中选取了23种最常消费的食品作为样本。采用气相色谱 - 质谱检测器分析食品中滴滴涕(DDTs)和六六六(HCHs)的浓度。食品中滴滴涕和六六六的残留量分别为0.95 - 3.53纳克/克和0.32 - 1.96纳克/克。有机氯农药(∑OCPs)残留量最高的是畜肉,为4.75纳克/克,最低的是面粉,为1.31纳克/克。无论性别如何,儿童的滴滴涕和六六六估计每日摄入量均高于其他年龄组。就食品类别而言,所有年龄组中,蔬菜消费导致的滴滴涕和六六六膳食暴露量高于其他食品类别,占总量的20.21% - 29.18%。所有人群的γ - 六六六和滴滴涕每日摄入量均远低于联合国粮食及农业组织/世界卫生组织建议的可接受量。健康风险评估表明,当地居民无明显非致癌风险,而癌症风险估计为10∼10,高于可接受风险水平且低于优先风险水平。在不同性别和年龄的居民中,各年龄组女性的风险均高于男性,儿童是最易受健康风险影响的年龄组。

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