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在枯草芽孢杆菌中，短重复序列之间的重组在质粒中比在染色体中更频繁。

Recombination between short repeated sequences is more frequent in plasmids than in the chromosome of Bacillus subtilis.

作者信息

Jannière L, Ehrlich S D

机构信息

Institut Jacques Monod, Paris, France.

出版信息

Mol Gen Genet. 1987 Nov;210(1):116-21. doi: 10.1007/BF00337766.

DOI:10.1007/BF00337766
PMID:2828888
Abstract

We measured in Bacillus subtilis the recombination frequency between directly repeated 9 bp sequences flanking the transposon Tn5. Four different repeats were analyzed. They recombined with frequencies between 10(-7) and 10(-6) when they were carried on plasmids, and 150-1500 times less frequently when they were carried on the chromosome. We propose that this difference is due to the generation of single stranded DNA during plasmid replication.

摘要

我们测定了枯草芽孢杆菌中转座子Tn5两侧直接重复的9bp序列之间的重组频率。分析了四种不同的重复序列。当它们存在于质粒上时，重组频率在10^(-7)到10^(-6)之间，而当它们存在于染色体上时，重组频率则低150 - 1500倍。我们认为这种差异是由于质粒复制过程中产生了单链DNA。

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1
Recombination between short repeated sequences is more frequent in plasmids than in the chromosome of Bacillus subtilis.在枯草芽孢杆菌中，短重复序列之间的重组在质粒中比在染色体中更频繁。
Mol Gen Genet. 1987 Nov;210(1):116-21. doi: 10.1007/BF00337766.
2
Recombination between repeated DNA sequences occurs more often in plasmids than in the chromosome of Bacillus subtilis.重复DNA序列之间的重组在质粒中比在枯草芽孢杆菌的染色体中更频繁发生。
Mol Gen Genet. 1984;197(1):46-54. doi: 10.1007/BF00327921.
3
Plasmid replication stimulates DNA recombination in Bacillus subtilis.质粒复制刺激枯草芽孢杆菌中的DNA重组。
J Mol Biol. 1987 Jul 5;196(1):39-48. doi: 10.1016/0022-2836(87)90509-2.
4
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Plasmid deletion formation between short direct repeats in Bacillus subtilis is stimulated by single-stranded rolling-circle replication intermediates.枯草芽孢杆菌中短直接重复序列间的质粒缺失形成受单链滚环复制中间体的刺激。
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Recombination between repeated DNA sequences occurs more often in plasmids than in the chromosome of Bacillus subtilis.重复DNA序列之间的重组在质粒中比在枯草芽孢杆菌的染色体中更频繁发生。
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Extremely large chromosomal deletions are intimately involved in genetic instability and genomic rearrangements in Streptomyces glaucescens.极大型染色体缺失与浅绿链霉菌的遗传不稳定性和基因组重排密切相关。
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Recombination between short direct repeats in a recA host.recA宿主中短直接重复序列之间的重组。
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Precise and nearly-precise excision of the symmetrical inverted repeats of Tn5; common features of recA-independent deletion events in Escherichia coli.Tn5对称反向重复序列的精确及近乎精确切除；大肠杆菌中不依赖recA的缺失事件的共同特征
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