• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Efficiency of homologous DNA recombination varies along the Bacillus subtilis chromosome.同源DNA重组的效率在枯草芽孢杆菌染色体上各部位有所不同。
J Bacteriol. 1988 Sep;170(9):3978-82. doi: 10.1128/jb.170.9.3978-3982.1988.
2
Recombination between repeated DNA sequences occurs more often in plasmids than in the chromosome of Bacillus subtilis.重复DNA序列之间的重组在质粒中比在枯草芽孢杆菌的染色体中更频繁发生。
Mol Gen Genet. 1984;197(1):46-54. doi: 10.1007/BF00327921.
3
[Construction of plasmids integrating into the Bacillus subtilis chromosome through homologous recombination and their use as integration vectors].[通过同源重组整合到枯草芽孢杆菌染色体中的质粒构建及其作为整合载体的应用]
Genetika. 1987 Mar;23(3):405-13.
4
Recombination between short repeated sequences is more frequent in plasmids than in the chromosome of Bacillus subtilis.在枯草芽孢杆菌中，短重复序列之间的重组在质粒中比在染色体中更频繁。
Mol Gen Genet. 1987 Nov;210(1):116-21. doi: 10.1007/BF00337766.
5
[Insertion of foreign functioning genes into bacterial chromosome: the construction of a hybrid molecule capable of recombination with Bacillus subtilis DNA from plasmid pBD 12 and phage phi 105 DNA].[将外源功能基因插入细菌染色体：构建一种能够与来自质粒pBD 12和噬菌体phi 105 DNA的枯草芽孢杆菌DNA进行重组的杂交分子]
Dokl Akad Nauk SSSR. 1982;264(4):976-9.
6
Integration and excision of a plasmid in Bacillus subtilis.枯草芽孢杆菌中质粒的整合与切除
Mol Gen Genet. 1981;182(1):99-105. doi: 10.1007/BF00422774.
7
Plasmid replication stimulates DNA recombination in Bacillus subtilis.质粒复制刺激枯草芽孢杆菌中的DNA重组。
J Mol Biol. 1987 Jul 5;196(1):39-48. doi: 10.1016/0022-2836(87)90509-2.
8
Stable gene amplification in the chromosome of Bacillus subtilis.枯草芽孢杆菌染色体中的稳定基因扩增。
Gene. 1985;40(1):47-55. doi: 10.1016/0378-1119(85)90023-x.
9
Integration of repeated sequences (pBR322) in the Bacillus subtilis 168 chromosome without affecting the genome structure.重复序列（pBR322）整合到枯草芽孢杆菌168染色体中，而不影响基因组结构。
Mol Gen Genet. 1993 Nov;241(3-4):287-97. doi: 10.1007/BF00284680.
10
[Integration of various plasmids into the Bacillus subtilis chromosome].[各种质粒整合到枯草芽孢杆菌染色体中]
Genetika. 1985 Oct;21(10):1618-26.

引用本文的文献

1
Bacillus SEVA siblings: A Golden Gate-based toolbox to create personalized integrative vectors for Bacillus subtilis.芽孢杆菌 SEVA 姊妹：基于 Golden Gate 的工具盒，用于构建枯草芽孢杆菌个性化整合载体。
Sci Rep. 2017 Oct 26;7(1):14134. doi: 10.1038/s41598-017-14329-5.
2
Single-crossover integration in the Lactobacillus sake chromosome and insertional inactivation of the ptsI and lacL genes.清酒乳杆菌染色体中的单交换整合以及ptsI和lacL基因的插入失活。
Appl Environ Microbiol. 1997 Jun;63(6):2117-23. doi: 10.1128/aem.63.6.2117-2123.1997.
3
High-efficiency gene inactivation and replacement system for gram-positive bacteria.革兰氏阳性菌的高效基因失活与替换系统
J Bacteriol. 1993 Jun;175(11):3628-35. doi: 10.1128/jb.175.11.3628-3635.1993.
4
Integration of repeated sequences (pBR322) in the Bacillus subtilis 168 chromosome without affecting the genome structure.重复序列（pBR322）整合到枯草芽孢杆菌168染色体中，而不影响基因组结构。
Mol Gen Genet. 1993 Nov;241(3-4):287-97. doi: 10.1007/BF00284680.
5
Integration and expression of alpha-amylase and endoglucanase genes in the Lactobacillus plantarum chromosome.α-淀粉酶和内切葡聚糖酶基因在植物乳杆菌染色体中的整合与表达。
Appl Environ Microbiol. 1989 Sep;55(9):2130-7. doi: 10.1128/aem.55.9.2130-2137.1989.
6
Stability of reiterated sequences in the Bacillus subtilis chromosome.枯草芽孢杆菌染色体中重复序列的稳定性
J Bacteriol. 1989 May;171(5):2653-6. doi: 10.1128/jb.171.5.2653-2656.1989.
7
Multiple copies of a bile acid-inducible gene in Eubacterium sp. strain VPI 12708.真杆菌属菌株VPI 12708中一个胆汁酸诱导基因的多个拷贝。
J Bacteriol. 1990 Aug;172(8):4420-6. doi: 10.1128/jb.172.8.4420-4426.1990.
8
Genetic exchange of transposon and integrative plasmid markers in Mycoplasma pulmonis.肺炎支原体中转座子和整合性质粒标记的基因交换
J Bacteriol. 1990 May;172(5):2267-72. doi: 10.1128/jb.172.5.2267-2272.1990.
9
Use of integrational plasmid excision to identify cellular localization of gene expression during sporulation in Bacillus subtilis.利用整合质粒切除来鉴定枯草芽孢杆菌孢子形成过程中基因表达的细胞定位。
J Bacteriol. 1990 Dec;172(12):6937-41. doi: 10.1128/jb.172.12.6937-6941.1990.
10
Replacement recombination in Lactococcus lactis.乳酸乳球菌中的置换重组。
J Bacteriol. 1991 Aug;173(15):4794-8. doi: 10.1128/jb.173.15.4794-4798.1991.

本文引用的文献

1
Mutations of Bacteria from Virus Sensitivity to Virus Resistance.细菌从对病毒敏感到对病毒抗性的突变。
Genetics. 1943 Nov;28(6):491-511. doi: 10.1093/genetics/28.6.491.
2
Recombination between repeated DNA sequences occurs more often in plasmids than in the chromosome of Bacillus subtilis.重复DNA序列之间的重组在质粒中比在枯草芽孢杆菌的染色体中更频繁发生。
Mol Gen Genet. 1984;197(1):46-54. doi: 10.1007/BF00327921.
3
Gene amplification in Bacillus subtilis.枯草芽孢杆菌中的基因扩增。
J Gen Microbiol. 1984 Jul;130(7):1613-21. doi: 10.1099/00221287-130-7-1613.
4
Roles of RecBC enzyme and chi sites in homologous recombination.RecBC酶和chi位点在同源重组中的作用。
Cold Spring Harb Symp Quant Biol. 1984;49:485-95. doi: 10.1101/sqb.1984.049.01.055.
5
Insertional mutagenesis in Bacillus subtilis: mechanism and use in gene cloning.枯草芽孢杆菌中的插入诱变：机制及其在基因克隆中的应用。
Gene. 1982 Oct;19(3):277-84. doi: 10.1016/0378-1119(82)90017-8.
6
Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies.pE194的核苷酸序列和功能图谱，pE194是一种质粒，可产生对大环内酯类、林可酰胺类和B型链阳菌素抗体的诱导抗性。
J Bacteriol. 1982 May;150(2):804-14. doi: 10.1128/jb.150.2.804-814.1982.
7
Recombination efficiency is a quadratic function of the length of homology during plasmid transformation of Bacillus subtilis protoplasts and Escherichia coli competent cells.在枯草芽孢杆菌原生质体和大肠杆菌感受态细胞的质粒转化过程中，重组效率是同源长度的二次函数。
EMBO J. 1984 Dec 1;3(12):2879-84. doi: 10.1002/j.1460-2075.1984.tb02224.x.
8
A novel method for the rapid cloning in Escherichia coli of Bacillus subtilis chromosomal DNA adjacent to Tn917 insertions.一种在大肠杆菌中快速克隆与Tn917插入位点相邻的枯草芽孢杆菌染色体DNA的新方法。
Mol Gen Genet. 1984;195(3):424-33. doi: 10.1007/BF00341443.
9
Thymidylate synthesis and aminopterin resistance in Bacillus subtilis.枯草芽孢杆菌中的胸苷酸合成与氨甲蝶呤抗性
J Bacteriol. 1966 Jul;92(1):186-96. doi: 10.1128/jb.92.1.186-196.1966.
10
Integration of linear, heterologous DNA molecules into the Bacillus subtilis chromosome: mechanism and use in induction of predictable rearrangements.线性异源DNA分子整合到枯草芽孢杆菌染色体中：机制及在诱导可预测重排中的应用。
J Bacteriol. 1985 Jul;163(1):111-20. doi: 10.1128/jb.163.1.111-120.1985.

同源DNA重组的效率在枯草芽孢杆菌染色体上各部位有所不同。

Efficiency of homologous DNA recombination varies along the Bacillus subtilis chromosome.

作者信息

Vagner V, Ehrlich S D

机构信息

Institut des Biotechnologies, Centre de Recherche de Jouy en Josas, France.

出版信息

J Bacteriol. 1988 Sep;170(9):3978-82. doi: 10.1128/jb.170.9.3978-3982.1988.

DOI:10.1128/jb.170.9.3978-3982.1988
PMID:3137211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC211398/
Abstract

Structures consisting of a genetic marker (erythromycin or kanamycin resistance, thymidylate synthetase) flanked by 3.4-kilobase direct repeats (pBR322 sequences) were inserted in 12 different locations of the Bacillus subtilis chromosome. Recombination between the repeats was followed by the loss of the genetic marker. Recombination frequencies found in different locations varied from 1.2 X 10(-5) to 40 X 10(-5) per cell generation. Such differences were highly significant (P less than 0.001).

摘要

由两侧带有3.4千碱基直接重复序列（pBR322序列）的遗传标记（红霉素或卡那霉素抗性、胸苷酸合成酶）组成的结构被插入枯草芽孢杆菌染色体的12个不同位置。重复序列之间的重组伴随着遗传标记的丢失。在不同位置发现的重组频率在每细胞世代1.2×10⁻⁵至40×10⁻⁵之间变化。这种差异非常显著（P小于0.001）。