获得性免疫缺陷综合征中的巨细胞病毒性视网膜炎和视神经炎。病例报告。

Cytomegalovirus retinitis and optic neuritis in acquired immune deficiency syndrome. Report of a case.

作者信息

Grossniklaus H E, Frank K E, Tomsak R L

机构信息

Division of Ophtalmology, University Hospitals of Cleveland, Case Western Reserve University, OH 44106.

出版信息

Ophthalmology. 1987 Dec;94(12):1601-4. doi: 10.1016/s0161-6420(87)33261-0.

DOI:10.1016/s0161-6420(87)33261-0

PMID:2829090

Abstract

A 33-year-old man with acquired immune deficiency syndrome (AIDS) was found to have bilateral cytomegalovirus (CMV) retinitis with concomitant unilateral optic neuritis. The patient died and postmortem examination of both eyes disclosed CMV inclusions in all layers of the involved retinas including the retinal pigment epithelium (RPE). Also found were CMV inclusions in the optic nerve of his left eye. Immunohistochemical stains for glial fibrillary acid protein demonstrated that glial cells were infected in the optic nerve.

摘要

一名33岁的获得性免疫缺陷综合征（艾滋病）男性患者被发现患有双侧巨细胞病毒（CMV）视网膜炎，并伴有单侧视神经炎。患者死亡，双眼尸检显示受累视网膜的所有层包括视网膜色素上皮（RPE）均有CMV包涵体。在其左眼视神经中也发现了CMV包涵体。胶质纤维酸性蛋白的免疫组织化学染色显示视神经中的神经胶质细胞被感染。