Department of Chemistry, The University of Texas at Austin , Austin, Texas 78712, United States.
J Am Chem Soc. 2017 Apr 5;139(13):4635-4638. doi: 10.1021/jacs.7b01008. Epub 2017 Mar 28.
A new autoinductive cascade employing benzoyl fluoride as a latent source of fluoride is reported for signal amplification and optical detection of fluoride. The autoinduction leads to a maximum 4-fold signal enhancement for each fluoride generated, as well as a self-propagating cycle that generates three fluorophores for each single fluoride released. A two-step integrated protocol creates a more rapid autoinductive cascade than previously reported, as well as a highly sensitive diagnostic assay for the ultratrace quantitation of a phosphoryl fluoride nerve agent surrogate.
本文报道了一种新的自动感应级联反应，该反应采用苯甲酰氟作为氟离子的潜在来源，用于氟离子的信号放大和光学检测。自动感应导致每个生成的氟离子的信号增强最大可达 4 倍，并且自传播循环为每个释放的单个氟离子生成三个荧光团。两步集成方案比以前报道的更快地产生自动感应级联，并且对痕量磷酸氟神经毒气模拟物进行超灵敏诊断分析。
