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Mobetron 2000术中放射治疗的调试、临床应用及性能

Commissioning, clinical implementation, and performance of the Mobetron 2000 for intraoperative radiation therapy.

作者信息

Wootton Landon S, Meyer Juergen, Kim Edward, Phillips Mark

机构信息

Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, USA.

出版信息

J Appl Clin Med Phys. 2017 Jan;18(1):230-242. doi: 10.1002/acm2.12027.

DOI:10.1002/acm2.12027
PMID:28291922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5689882/
Abstract

The Mobetron is a mobile electron accelerator designed to deliver therapeutic radiation dose intraoperatively while diseased tissue is exposed. Experience with the Mobetron 1000 has been reported extensively. However, since the time of those publications a new model, the Mobetron 2000, has become commercially available. Experience commissioning this new model and 3 years of data from historical use are reported here. Descriptions of differences between the models are emphasized, both in physical form and in dosimetric characteristics. Results from commissioning measurements including output factors, air gap factors, percent depth doses (PDDs), and 2D dose profiles are reported. Output factors are found to have changed considerably in the new model, with factors as high as 1.7 being measured. An example lookup table of appropriate accessory/energy combinations for a given target dimension is presented, and the method used to generate it described. Results from 3 years of daily QA measurements are outlined. Finally, practical considerations garnered from 3 years of use are presented.

摘要

Mobetron是一种移动式电子加速器,设计用于在术中暴露病变组织时提供治疗性辐射剂量。关于Mobetron 1000的使用经验已有广泛报道。然而,自这些出版物发表以来,一种新型号Mobetron 2000已投入商业使用。本文报告了调试这种新型号的经验以及3年的历史使用数据。文中强调了两种型号在物理形式和剂量学特征方面的差异。报告了调试测量结果,包括输出因子、气隙因子、百分深度剂量(PDD)和二维剂量分布。发现新型号的输出因子有很大变化,测量到的因子高达1.7。给出了一个针对给定靶区尺寸的合适附件/能量组合的示例查找表,并描述了生成该表的方法。概述了3年每日质量保证测量的结果。最后,介绍了3年使用过程中积累的实际经验。

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Early invasive cancer and partial intraoperative electron radiation therapy of the breast: experience of the jules bordet institute.
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