Sabouri Mohammad Rasoul, Kazemnezhad Ehsan, Hafezi Vahideh
Guilan University of Medical Sciences, Rasht, Iran.
Med Hypothesis Discov Innov Ophthalmol. 2016 Fall;5(3):104-111.
We aimed to determine normal macular thickness using Cirrus high definition optical coherence tomography. In this cross-sectional survey, 112 subjects were selected using random sampling from the Rasht telephone directory. All subjects underwent complete eye examinations. Both eyes of each patient were evaluated. The creation of a macular thickness map using a macular cube 512 × 128 combo was optional. The average thickness of the retina was determined in 9 Early Treatment Diabetic Retinopathy Study (ETDRS) regions. To assess reproducibility and system reliability, the thickness of the retina was measured up to 5 times in 10 healthy subjects. The coefficient of variation was then calculated for each individual. The coefficient of variation of macular thickness within 1 mm of the center was 0.15 - 1.33%. The means and standard deviations of central subfield thickness (CST), macular thickness (MT), and macular volume (MV) were 245.44 ± 20.39 µm, 277.9 ± 12.0 µm, and 9.98 ± 0.43 mm, respectively. The mean CST (P < 0.0001), MT (P = 0.038), and MV (P = 0.030) were significantly higher in men than in women. In addition, regardless of age or sex, macular thickness increased when moving from within 1 mm of the center to 3 mm and 6 mm away from the center, so that the upper 3 mm (S3) was the thickest region, and the temporal 6 mm (T6) was the thinnest region in the ETDRS regions. The mean MT of healthy subjects was 280.67 ± 12.79 µm in men and 276.63 ± 11.61 µm in women. Therefore, the macula is significantly thicker in men than in women (P = 0.038).
我们旨在使用Cirrus高清光学相干断层扫描技术测定正常黄斑厚度。在这项横断面调查中，从拉什特电话簿中随机抽样选取了112名受试者。所有受试者均接受了全面的眼部检查。对每位患者的双眼进行了评估。使用黄斑立方体512×128组合创建黄斑厚度图为可选操作。在9个早期糖尿病性视网膜病变研究（ETDRS）区域测定视网膜的平均厚度。为评估可重复性和系统可靠性，对10名健康受试者的视网膜厚度进行了多达5次测量。然后计算每个个体的变异系数。中心1毫米范围内黄斑厚度的变异系数为0.15 - 1.33%。中心子区域厚度（CST）、黄斑厚度（MT）和黄斑体积（MV）的均值和标准差分别为245.44±20.39 µm、277.9±12.0 µm和9.98±0.43 mm。男性的平均CST（P < 0.0001）、MT（P = 0.038）和MV（P = 0.030）显著高于女性。此外，无论年龄或性别，从中心1毫米范围内向中心3毫米和6毫米处移动时，黄斑厚度增加，因此在ETDRS区域中，上方3毫米（S3）是最厚的区域，颞侧6毫米（T6）是最薄的区域。健康男性受试者的平均MT为280.67±12.79 µm，女性为276.63±11.61 µm。因此，男性的黄斑明显比女性厚（P = 0.038）。
