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[使用时域和频域光学相干断层扫描技术比较九个黄斑亚区的厚度值]

[Comparison of thickness values in nine macular subfields using time-domain and spectral-domain optical coherence tomography].

作者信息

Schneider Miklós, Szekeres Orsolya, Kiss Huba, Kis Mária, Papp András, Németh János

机构信息

Semmelweis Egyetem, Általános Orvostudományi Kar Szemészeti Klinika Budapest Mária u. 39. 1085.

Budapesti Gazdasági Főiskola Külkereskedelmi Kar Budapest.

出版信息

Orv Hetil. 2013 Dec 29;154(52):2059-64. doi: 10.1556/OH.2013.29785.

DOI:10.1556/OH.2013.29785
PMID:24374581
Abstract

AIM

To compare macular thickness measurements with spectral-domain (Cirrus HD-OCT) and time-domain (StratusOCT) optical coherence tomography.

METHOD

Macular thickness was measured in nine ETDRS subfields in the same eye of 20 healthy subjects using both instruments. Using Cirrus HD-OCT both the Macular Cube 512×128 and Macular Cube 200×200 protocol, using StratusOCT the Fast Macular Thickness Map protocol was performed. Reproducibility of all three measurement series was assessed and the average of the measurement series was compared on each field.

RESULTS

Measurement values obtained by StratusOCT were significantly lower than those obtained by Cirrus HD-OCT (p<0.001) in all subfields. Correlation coefficient between the results obtained by the two protocols of Cirrus HD-OCT was 0.977.

CONCLUSIONS

By using Cirrus HD-OCT we could observe better repeatability than with StratusOCT. Using Cirrus HD-OCT significantly higher measurement values could be obtained in all subfields than those measured with Stratus. Using different OCT instruments we get significantly different values, therefore care needs to be taken when comparing data.

摘要

目的

比较使用光谱域(Cirrus HD-OCT)和时域(Stratus OCT)光学相干断层扫描测量黄斑厚度的情况。

方法

使用这两种仪器对20名健康受试者同一只眼睛的9个早期糖尿病性视网膜病变研究(ETDRS)子区域测量黄斑厚度。使用Cirrus HD-OCT的黄斑立方体512×128和黄斑立方体200×200协议,使用Stratus OCT的快速黄斑厚度图协议。评估所有三个测量系列的可重复性,并比较每个区域测量系列的平均值。

结果

在所有子区域中,Stratus OCT获得的测量值显著低于Cirrus HD-OCT获得的测量值(p<0.001)。Cirrus HD-OCT两种协议获得的结果之间的相关系数为0.977。

结论

与Stratus OCT相比,使用Cirrus HD-OCT可观察到更好的重复性。使用Cirrus HD-OCT在所有子区域均可获得显著高于Stratus测量值的测量值。使用不同的OCT仪器会得到显著不同的值,因此在比较数据时需谨慎。

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